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Extracellular Mitochondrial ATP, Suramin, and Autism?
Clinical Therapeutics, 2013& 2013 Elsevier HS Journals, Inc. All rights reserved. A recent publication reported that pregnant mice injected with the viral-like material Poly(I:C) produced, as previously known, offspring that exhibit behavior reminiscent of autism; it also reported that therapy with the antipurinergic drug suramin, used to treat the African disease ...
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Adenosine triphosphate (ATP) is the primary energy source and storage molecule within eukaryotic cells, acting as a donor in most endergonic reactions. For this reason, its intracellular concentration typically ranges between 5 and 10 millimolar. In contrast, the extracellular ATP (eATP) concentration is very low (nanomolar) due to the absence of ...
Anna Pegoraro +4 more
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Anna Pegoraro +4 more
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Extracellular ATP and Adenosine in Cancer Pathogenesis and Treatment
Trends in Cancer, 2021Gulam Manji +2 more
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Role of ATP in Extracellular Vesicle Biogenesis and Dynamics
Frontiers in Pharmacology, 2021Marta Lombardi +2 more
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[The role of extracellular ATP in the airway].
Sheng li ke xue jin zhan [Progress in physiology], 2012ATP serves not only as an energy source for all cell types but as an extracellular messenger for autocrine and paracrine signaling involving in a versatile role in modulating various cellular functions. This review summarizes the efflux pathways of ATP released from airway epithelial cells, the signal pathways through which ATP induces ion transport by
Hong-Mei, Guo +2 more
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