Results 71 to 80 of about 673,761 (305)

Isolation and Screening of Extracellular Protease Enzyme from Fungal Isolates of Soil

, 2018
Protease is an enzyme that conducts proteolysis and receives high attention as the most important enzyme in many industries. The enzymes find applications in waste treatment, bioremediation process, detergents and leather industry.
Abdalla Mohamed Abdullah Maitig, Kartikya Tiwari, Mohamed A.M. Alhoot   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones [PDF]

, 2013
Neutrophil extracellular traps are networks of DNA and associated proteins produced by nucleosome release from activated neutrophils in response to infection stimuli and have recently been identified as key mediators between innate immunity, inflammation,
Szabó, László, Szab , L., Hoell, Armin, Kolev, Krasimir, Sótonyi, Péter, Longstaff, C., Longstaff C, Krumrey, M., Komorowicz, E., Longstaff, Colin, Varjú, Imre, Kolev, K., Varga, Z., Kolev, Kraszimir Nikolaev, Komorowicz, Erzsébet, Krumrey, Michael, Hoell A, S tonyi, P., Krumrey M, Varju, I., Hoell, A., Bóta, Attila, Varga, Zoltán, B ta, A.   +23 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Characterization of Hexenuronosyl Xylan-degrading Enzymes Produced by Paenibacillus sp. 07

BioResources, 2016
The enzyme involved in hexenuronic acid (HexA) removal from kraft pulp was identified in Paenibacillus sp. strain 07. Extracellular and intracellular enzymes of Paenibacillus sp. were assessed for their hexenuronosyl-xylotriose (∆X3) degradation activity.
Krisna Septiningrum, Hiroshi Ohi, Akiko Nakagawa-izumi, Akihiko Kosugi   +3 more
doaj   +1 more source

Extracellular Enzyme Secretion by Pseudomonas lemoignei [PDF]

Journal of Bacteriology, 1974
The ability of succinate to repress the secretion of Pseudomonas lemoignei poly-β-hydroxybutyrate depolymerase was a function of pH. Repression only occurred when the pH of the medium was 7.0 or less. At a higher pH, lack of sensitivity to succinate concentration may have been due to a limited ability to transport ...
M W, Stinson, J M, Merrick
openaire   +2 more sources

Extracellular enzyme kinetics and thermodynamics along a climate gradient in southern California [PDF]

, 2017
Microbial decomposers produce extracellular enzymes to degrade complex plant polymers, making plant C available for metabolism and eventual respiration back to the atmosphere as CO2.
Steven D. Allison, Nameer R. Baker, Baker, Nameer R, Allison, Steven D   +3 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Studies on the regulation of extracellular collagenase production by vibrio alginolyticus

, 1981
Bibliography: leaves 117-133.Vibrio alginolyticus synthesized extracellular collagenase in a highly aerated peptone medium at the late-exponential and early-stationary phases of growth.
Reid, Graham Charlton
core