Results 91 to 100 of about 1,499,817 (257)

Characterization of Extracellular Penicilin G Acylase Produced by A New Local Strain of Bacillus subtilis BAC4

Hayati Journal of Biosciences, 2008
Penicillin G acylase (PGA) which catalyses penicillin G hydrolysis reaction is a key enzyme for the industrial production of penicilin G derivatives used in therapeutics.
SUPARTONO, ENNY RATNANINGSIH, SADIJAH ACHMAD, OEI BAN LIANG   +3 more
doaj   +3 more sources

Decoupling between the genetic potential and the metabolic regulation and expression in microbial organic matter cleavage across microbiomes

Microbiology Spectrum
Metagenomics, metatranscriptomics, and metaproteomics are used to explore the microbial capability of enzyme secretion, but the links between protein-encoding genes and corresponding transcripts/proteins across ecosystems are underexplored. By conducting
Zihao Zhao, Federico Baltar, Gerhard J. Herndl   +2 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Global Regulators ExpA (GacA) and KdgR Modulate Extracellular Enzyme Gene Expression Through the RsmA-rsmB System in Erwinia carotovora subsp. carotovora

Molecular Plant-Microbe Interactions, 2001
The production of the main virulence determinants, the extracellular plant cell wall-degrading enzymes, and hence virulence of Erwinia carotovora subsp. carotovora is controlled by a complex regulatory network.
Heidi Hyytiäinen, Marcos Montesano, E. Tapio Palva   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]

, 2013
Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
E. Buzás, A. Falus, Á. Kittel, Buzás, E., Kittel, Ágnes, Falus, A.   +5 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Extracellular enzyme activities of strains from clades 1–4 grown at different NaCl concentrations at 24°C.

, 2015
+, all tested strains showed measurable enzyme activity;–, no tested strain showed measurable enzyme activity; +/–, 50% or more tested strains showed measurable enzyme activity;–/+, 50% or less showed measurable enzyme activity; n, number of tested ...
Nina Gunde-Cimerman (494801), Hans-Josef Schroers (745984), Polona Zalar (536680), Sašo Jančič (709515), Keith A. Seifert (709517), Jens C. Frisvad (210022), Hai D. T. Nguyen (709514)   +6 more
core   +1 more source

Fungal Biodegradation of Procyanidin in Submerged Fermentation

Fermentation
The coffee industry generates a large amount of waste that is difficult to treat due to its chemical composition, namely, the presence of caffeine and its derivatives, as well as recalcitrant molecules such as tannins (mainly condensed tannins or ...
Leidy Johana Valencia-Hernández, Jorge E. Wong-Paz, J. Alberto Ascacio-Valdés, Arely Prado-Barragan, Mónica L. Chávez-González, Cristóbal N. Aguilar   +5 more
doaj   +1 more source

Extracellular Enzymes Produced by Marine Eukaryotes, Thraustochytrids

Bioscience, Biotechnology, and Biochemistry, 2009
Extracellular enzymes produced by six strains of thraustochytrids, Thraustochytrium, Schizochytrium, and Aurantiochytrium, were investigated. These strains produced 5 to 8 kinds of the extracellular enzymes, depending on the species. Only the genus Thraustochytrium produced amylase.
TAOKA, Yousuke, NAGANO, Naoki, OKITA, Yuji, IZUMIDA, Hitoshi, SUGIMOTO, Shinichi, HAYASHI, Masahiro   +5 more
openaire   +2 more sources