Results 1 to 10 of about 2,881,986 (357)

Analysis of extracellular RNA in cerebrospinal fluid [PDF]

Journal of Extracellular Vesicles, 2017
We examined the extracellular vesicle (EV) and RNA composition of pooled normal cerebrospinal fluid (CSF) samples and CSF from five major neurological disorders: Alzheimer’s disease (AD), Parkinson’s disease (PD), low-grade glioma (LGG), glioblastoma ...
Julie A. Saugstad, Theresa A. Lusardi, Kendall R. Van Keuren-Jensen, Jay I. Phillips, Babett Lind, Christina A. Harrington, Trevor J. McFarland, Amanda L. Courtright, Rebecca A. Reiman, Ashish S. Yeri, M. Yashar S. Kalani, P. David Adelson, Jorge Arango, John P. Nolan, Erika Duggan, Karen Messer, Johnny C. Akers, Douglas R. Galasko, Joseph F. Quinn, Bob S. Carter, Fred H. Hochberg   +20 more
doaj   +5 more sources

New insights in addressing cerebral small vessel disease: Associated with extracellular fluid in white matter [PDF]

Frontiers in Neuroscience, 2022
ObjectiveTo explore the role of extracellular fluid, assessed by diffusion tensor imaging (DTI) metrics of free water (FW), in the white matter of patients with cerebral small vessel disease (CSVD).Materials and methodsThe baseline clinical and imaging ...
Haiyuan Lan, Xinjun Lei, Zhihua Xu, Songkuan Chen, Wanfeng Gong, Yunqi Cai   +5 more
doaj   +2 more sources

The extracellular volume status predicts body fluid response to SGLT2 inhibitor dapagliflozin in diabetic kidney disease

Diabetology & Metabolic Syndrome, 2020
Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors are an antihyperglycemic drug with diuretic action. We recently reported that the SGLT2 inhibitor dapagliflozin ameliorates extracellular volume expansion with a mild increase in urine volume ...
Ken Ohara, Takahiro Masuda, Masato Morinari, Mari Okada, Atsushi Miki, Saki Nakagawa, Takuya Murakami, Kentaro Oka, Maki Asakura, Yasuharu Miyazawa, Akito Maeshima, Tetsu Akimoto, Osamu Saito, Daisuke Nagata   +13 more
doaj   +2 more sources

Extracellular Fluid Flow Induces Shallow Quiescence Through Physical and Biochemical Cues [PDF]

Frontiers in Cell and Developmental Biology, 2022
The balance between cell quiescence and proliferation is fundamental to tissue physiology and homeostasis. Recent studies have shown that quiescence is not a passive and homogeneous state but actively maintained and heterogeneous.
Bi Liu, Bi Liu, Xia Wang, Xia Wang, Linan Jiang, Jianhua Xu, Yitshak Zohar, Guang Yao   +7 more
doaj   +2 more sources

The plasticity of extracellular fluid homeostasis in insects [PDF]

Journal of Experimental Biology, 2016
ABSTRACTIn chemistry, the ratio of all dissolved solutes to the solution's volume yields the osmotic concentration. The present Review uses this chemical perspective to examine how insects deal with challenges to extracellular fluid (ECF) volume, solute content and osmotic concentration (pressure). Solute/volume plots of the ECF (hemolymph) reveal that
K. Beyenbach
openaire   +4 more sources

Blastopore gating mechanism to regulate extracellular fluid excretion [PDF]

iScience, 2023
Summary: Fluid uptake and efflux play roles in early embryogenesis as well as in adult homeostasis. Multicellular organisms have two main pathways for fluid movement: cellular-level, such as transcellular and paracellular pathways, and tissue-level ...
Soichiro Kato, Hidehiko Inomata
doaj   +2 more sources

Membrane Ruffling is a Mechanosensor of Extracellular Fluid Viscosity. [PDF]

Nat Phys, 2022
Pittman M, Iu E, Li K, Wang M, Chen J, Taneja N, Jo MH, Park S, Jung WH, Liang L, Barman I, Ha T, Gaitanaros S, Liu J, Burnette D, Plotnikov S, Chen Y.   +16 more
europepmc   +2 more sources

Extracellular fluid viscosity enhances cell migration and cancer dissemination. [PDF]

Nature, 2022
Bera K, Kiepas A, Godet I, Li Y, Mehta P, Ifemembi B, Paul CD, Sen A, Serra SA, Stoletov K, Tao J, Shatkin G, Lee SJ, Zhang Y, Boen A, Mistriotis P, Gilkes DM, Lewis JD, Fan CM, Feinberg AP, Valverde MA, Sun SX, Konstantopoulos K.   +22 more
europepmc   +2 more sources

Cryo-electron microscopy of extracellular vesicles from cerebrospinal fluid.

PLoS ONE, 2020
Extracellular vesicles (EVs) are membrane-enclosed vesicles which play important role for cell communication and physiology. EVs are found in many human biological fluids, including blood, breast milk, urine, cerebrospinal fluid (CSF), ejaculate, saliva ...
Anton Emelyanov, Tatiana Shtam, Roman Kamyshinsky, Luiza Garaeva, Nikolai Verlov, Irina Miliukhina, Anastasia Kudrevatykh, Gaspar Gavrilov, Yulia Zabrodskaya, Sofya Pchelina, Andrey Konevega   +10 more
doaj   +2 more sources

Extracellular fluid tonicity impacts sickle red blood cell deformability and adhesion.

Blood, 2017
Abnormal sickle red blood cell (sRBC) biomechanics, including pathological deformability and adhesion, correlate with clinical severity in sickle cell disease (SCD). Clinical intravenous fluids (IVFs) of various tonicities are often used during treatment
Carden MA, Fay ME, Lu X, Mannino RG, Sakurai Y, Ciciliano JC, Hansen CE, Chonat S, Joiner CH, Wood DK, Lam WA.   +10 more
europepmc   +2 more sources