Results 1 to 10 of about 3,572,587 (295)

Extracellular fluid viscosity enhances cell migration and cancer dissemination [PDF]

open access: yesNature, 2022
Cells respond to physical stimuli, such as stiffness 1 , fluid shear stress 2 and hydraulic pressure 3 , 4 . Extracellular fluid viscosity is a key physical cue that varies under physiological and pathological conditions, such as cancer 5 .
K. Bera   +22 more
semanticscholar   +2 more sources

New insights in addressing cerebral small vessel disease: Associated with extracellular fluid in white matter [PDF]

open access: yesFrontiers in Neuroscience, 2022
ObjectiveTo explore the role of extracellular fluid, assessed by diffusion tensor imaging (DTI) metrics of free water (FW), in the white matter of patients with cerebral small vessel disease (CSVD).Materials and methodsThe baseline clinical and imaging ...
Haiyuan Lan   +5 more
doaj   +2 more sources

The extracellular volume status predicts body fluid response to SGLT2 inhibitor dapagliflozin in diabetic kidney disease

open access: yesDiabetology & Metabolic Syndrome, 2020
Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors are an antihyperglycemic drug with diuretic action. We recently reported that the SGLT2 inhibitor dapagliflozin ameliorates extracellular volume expansion with a mild increase in urine volume ...
Ken Ohara   +13 more
doaj   +2 more sources

Cryo-electron microscopy of extracellular vesicles from cerebrospinal fluid.

open access: yesPLoS ONE, 2020
Extracellular vesicles (EVs) are membrane-enclosed vesicles which play important role for cell communication and physiology. EVs are found in many human biological fluids, including blood, breast milk, urine, cerebrospinal fluid (CSF), ejaculate, saliva ...
Anton Emelyanov   +10 more
doaj   +2 more sources

BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles [PDF]

open access: goldMolecular Therapy: Nucleic Acids, 2013
Development of biofluid-based molecular diagnostic tests for cancer is an important step towards tumor characterization and real-time monitoring in a minimally invasive fashion.
Walter W. Chen   +16 more
openalex   +2 more sources

Analysis of extracellular RNA in cerebrospinal fluid

open access: yesJournal of Extracellular Vesicles, 2017
We examined the extracellular vesicle (EV) and RNA composition of pooled normal cerebrospinal fluid (CSF) samples and CSF from five major neurological disorders: Alzheimer’s disease (AD), Parkinson’s disease (PD), low-grade glioma (LGG), glioblastoma ...
Julie A. Saugstad   +20 more
doaj   +2 more sources

Comparison of body water status and its distribution in patients with non-septic infection, patients with sepsis, and healthy controls [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2021
Objective Although fluid resuscitation is the cornerstone of treatment for sepsis, the role of body water status in sepsis is poorly understood. This study aimed to understand how body water and its distribution are modified in patients with sepsis and ...
Jieun Shin   +8 more
doaj   +1 more source

Clinical Utility of Fluid Volume Assessment in Heart Failure Patients Using Bioimpedance Spectroscopy

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Bioimpedance spectroscopy (BIS) is a non-invasive method used to measure fluid volumes. In this report, we compare BIS measurements from patients with heart failure (HF) to those from healthy adults, and describe how these point-of-care fluid
Andrew J. Accardi   +4 more
doaj   +1 more source

Impact of Decreased Visibility of Deep Medullary Veins on White Matter Integrity in Patients with Cerebral Small Vessel Disease

open access: yesJournal of Integrative Neuroscience, 2023
Background: Based on susceptibility-weighted imaging (SWI) visibility, deep medullary vein (DMV) scores are related to white matter damage (WMD) in patients with cerebral small vessel disease (CSVD).
Huimei Wang   +6 more
doaj   +1 more source

Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies

open access: yesJournal of Extracellular Vesicles, 2023
Cerebrospinal fluid (CSF) is a clear, transparent fluid derived from blood plasma that protects the brain and spinal cord against mechanical shock, provides buoyancy, clears metabolic waste and transports extracellular components to remote sites in the ...
U. Sandau   +21 more
semanticscholar   +1 more source

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