Results 1 to 10 of about 1,191,682 (356)

Extracellular Matrix of Echinoderms

open access: yesMarine Drugs, 2023
This review considers available data on the composition of the extracellular matrix (ECM) in echinoderms. The connective tissue in these animals has a rather complex organization.
Igor Yu. Dolmatov   +1 more
doaj   +3 more sources

Extracellular Vesicles as Regulators of the Extracellular Matrix

open access: yesBioengineering, 2023
Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids, proteins, and lipids to facilitate cell-to-cell communication.
Neil J. Patel   +2 more
doaj   +3 more sources

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]

open access: yes, 2015
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Abraham, D   +11 more
core   +14 more sources

Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans

open access: yeseLife, 2023
The amyloid beta (Aβ) plaques found in Alzheimer’s disease (AD) patients’ brains contain collagens and are embedded extracellularly. Several collagens have been proposed to influence Aβ aggregate formation, yet their role in clearance is unknown.
Elisabeth Jongsma   +3 more
doaj   +1 more source

Extracellular matrix [PDF]

open access: yesFEBS Letters, 1990
A succinct overview of recent results on the biochemistry of extracellular matrix (ECM) is presented. The rapid expansion of this discipline over the best decades renders impossible to give an even approximately complete coverage of matrix biology. Some selected results concerning the four major families of macromolecules composing the ECM, that is ...
Labat-Robert, J.   +2 more
openaire   +2 more sources

Exposure to Bacteriophages T4 and M13 Increases Integrin Gene Expression and Impairs Migration of Human PC-3 Prostate Cancer Cells

open access: yesAntibiotics, 2021
The interaction between bacteriophages and integrins has been reported in different cancer cell lines, and efforts have been undertaken to understand these interactions in tumor cells along with their possible role in gene alterations, with the aim to ...
Swapnil Ganesh Sanmukh   +9 more
doaj   +1 more source

Bacteriophages M13 and T4 Increase the Expression of Anchorage-Dependent Survival Pathway Genes and Down Regulate Androgen Receptor Expression in LNCaP Prostate Cell Line

open access: yesViruses, 2021
Wild-type or engineered bacteriophages have been reported as therapeutic agents in the treatment of several types of diseases, including cancer. They might be used either as naked phages or as carriers of antitumor molecules.
Swapnil Ganesh Sanmukh   +8 more
doaj   +1 more source

The extracellular matrix in development [PDF]

open access: yesDevelopment, 2020
ABSTRACT As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides both physical support and signaling regulation to cells. Some ECM molecules provide a fibrillar environment around cells, while others provide a sheet-like basement membrane scaffold beneath epithelial cells.
David A. Cruz Walma, Kenneth M. Yamada
openaire   +3 more sources

The Evolution of Extracellular Matrix [PDF]

open access: yesMolecular Biology of the Cell, 2010
We present a perspective on the molecular evolution of the extracellular matrix (ECM) in metazoa that draws on research publications and data from sequenced genomes and expressed sequence tag libraries. ECM components do not function in isolation, and the biological ECM system or “adhesome” also depends on posttranslational processing enzymes, cell ...
Özbek, S   +4 more
openaire   +4 more sources

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