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The extracellular matrix in development [PDF]

open access: yesDevelopment, 2020
As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides both physical support and signaling regulation to cells. Some ECM molecules provide a fibrillar environment around cells, while others provide a sheet-like basement
D. Walma, Kenneth M. Yamada
semanticscholar   +4 more sources

The extracellular matrix at a glance [PDF]

open access: yesJournal of Cell Science, 2010
![Figure][1] The extracellular matrix (ECM) is the non-cellular component present within all tissues and organs, and provides not only essential physical scaffolding for the cellular constituents but also initiates crucial biochemical and biomechanical cues that are required for ...
C. Frantz, K. Stewart, V. Weaver
semanticscholar   +4 more sources

Extracellular Matrix of Echinoderms

open access: yesMarine Drugs, 2023
This review considers available data on the composition of the extracellular matrix (ECM) in echinoderms. The connective tissue in these animals has a rather complex organization.
Igor Yu. Dolmatov   +1 more
doaj   +3 more sources

Extracellular Vesicles as Regulators of the Extracellular Matrix

open access: yesBioengineering, 2023
Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids, proteins, and lipids to facilitate cell-to-cell communication.
Neil J. Patel   +2 more
doaj   +3 more sources

Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments

open access: yesMolecular Cancer, 2023
The malignant tumor is a multi-etiological, systemic and complex disease characterized by uncontrolled cell proliferation and distant metastasis. Anticancer treatments including adjuvant therapies and targeted therapies are effective in eliminating ...
Zhennan Yuan   +8 more
semanticscholar   +1 more source

The extracellular matrix and the immune system: A mutually dependent relationship

open access: yesScience, 2023
For decades, immunologists have studied the role of circulating immune cells in host protection, with a more recent appreciation of immune cells resident within the tissue microenvironment and the intercommunication between nonhematopoietic cells and ...
T. Sutherland, D. Dyer, J. Allen
semanticscholar   +1 more source

Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans

open access: yeseLife, 2023
The amyloid beta (Aβ) plaques found in Alzheimer’s disease (AD) patients’ brains contain collagens and are embedded extracellularly. Several collagens have been proposed to influence Aβ aggregate formation, yet their role in clearance is unknown.
Elisabeth Jongsma   +3 more
doaj   +1 more source

Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy

open access: yesJournal of Hematology & Oncology, 2022
Cancer microenvironment is critical for tumorigenesis and cancer progression. The extracellular matrix (ECM) interacts with tumor and stromal cells to promote cancer cells proliferation, migration, invasion, angiogenesis and immune evasion.
Yangfu Jiang   +5 more
semanticscholar   +1 more source

Exposure to Bacteriophages T4 and M13 Increases Integrin Gene Expression and Impairs Migration of Human PC-3 Prostate Cancer Cells

open access: yesAntibiotics, 2021
The interaction between bacteriophages and integrins has been reported in different cancer cell lines, and efforts have been undertaken to understand these interactions in tumor cells along with their possible role in gene alterations, with the aim to ...
Swapnil Ganesh Sanmukh   +9 more
doaj   +1 more source

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