Results 1 to 10 of about 717,294 (320)
Extracellular Vesicles as Regulators of the Extracellular Matrix
Bioengineering, 2023 Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids, proteins, and lipids to facilitate cell-to-cell communication.
Neil J. Patel +2 more
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Extracellular matrix and schistosomiasis [PDF]
Memorias do Instituto Oswaldo Cruz, 1991 Zilton A. Andrade
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Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans
eLife, 2023 The amyloid beta (Aβ) plaques found in Alzheimer’s disease (AD) patients’ brains contain collagens and are embedded extracellularly. Several collagens have been proposed to influence Aβ aggregate formation, yet their role in clearance is unknown.
Elisabeth Jongsma +3 more
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FEBS Letters, 1990 A succinct overview of recent results on the biochemistry of extracellular matrix (ECM) is presented. The rapid expansion of this discipline over the best decades renders impossible to give an even approximately complete coverage of matrix biology. Some selected results concerning the four major families of macromolecules composing the ECM, that is ...
Labat-Robert, J. +2 more
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Antibiotics, 2021 The interaction between bacteriophages and integrins has been reported in different cancer cell lines, and efforts have been undertaken to understand these interactions in tumor cells along with their possible role in gene alterations, with the aim to ...
Swapnil Ganesh Sanmukh +9 more
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Viruses, 2021 Wild-type or engineered bacteriophages have been reported as therapeutic agents in the treatment of several types of diseases, including cancer. They might be used either as naked phages or as carriers of antitumor molecules.
Swapnil Ganesh Sanmukh +8 more
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The extracellular matrix in development [PDF]
Development, 2020 ABSTRACT As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides both physical support and signaling regulation to cells. Some ECM molecules provide a fibrillar environment around cells, while others provide a sheet-like basement membrane scaffold beneath epithelial cells.
David A. Cruz Walma, Kenneth M. Yamada
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Frontiers in Aging, 2022 Aging is one of the largest risk factors for cancer, type 2 diabetes, osteoarthritis, cardiovascular diseases, and other age-related pathologies. Here, we give a detailed description of the interplay of chronic age-related pathologies with the remodeling
Tinka Vidović, Collin Y. Ewald
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The Evolution of Extracellular Matrix [PDF]
Molecular Biology of the Cell, 2010 We present a perspective on the molecular evolution of the extracellular matrix (ECM) in metazoa that draws on research publications and data from sequenced genomes and expressed sequence tag libraries. ECM components do not function in isolation, and the biological ECM system or “adhesome” also depends on posttranslational processing enzymes, cell ...
Özbek, S +4 more
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The Role of Cell-Matrix Interactions in Connective Tissue Mechanics [PDF]
, 2021 Living tissue is able to withstand large stresses in everyday life, yet it also actively adapts to dynamic loads. This remarkable mechanical behaviour emerges from the interplay between living cells and their non-living extracellular environment. Here we review recent insights into the biophysical mechanisms involved in the reciprocal interplay between
arxiv +1 more source