Results 131 to 140 of about 1,191,682 (356)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Regulation of rat mammary gene expression by extracellular matrix components [PDF]

, 1987
Joanne L. Blum, Mary E. Zeigler, Max S. Wicha   +2 more
openalex   +1 more source

Characterization and Biocompatibility Study of Nematic and Cholesteryl Liquid Crystals. [PDF]

, 2009
noIntensive research in bio-engineering has been conducted in the search for flexible biomaterials that could support cell growth and cells attachment.
Batista Lobo, Samira, Berends, Rebecca F., Blagden, Nicholas, Denyer, Morgan C.T., Javid, Farideh A., Soon, Chin Fhong, Youseffi, Mansour   +6 more
core   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Bone cell functions in PPIB knock-out mouse model for type IX osteogenesis imperfecta are distinct from classical dominant OI

Bone Reports, 2021
Ying Liu, Theresa Hefferan, Nadja Fratzl-Zelman, Joan Marini   +3 more
doaj   +1 more source

Substrate‐dependent differences in production of extracellular matrix molecules by squamous carcinoma cells and diploid fibroblasts [PDF]

, 1989
James Varani, Suzanne Fligiel, D. R. Inman, David L. Helmreich, Matthew J. Bendelow, William Hillegas   +5 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Extracellular matrix vesicles in human osteogenic neoplasms: An ultrastructural and enzymatic study [PDF]

, 1981
J. Sela, I. Bab, András Mühlrád, H Stein   +3 more
openalex   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

CRTAP-Null Osteoblasts Have Increased Proliferation, Protein Secretion, and Skeletal Morphogenesis Gene Expression with Downregulation of Cellular Adhesion

Cells
Type VII osteogenesis imperfecta (OI), caused by recessive CRTAP mutations, is predominantly lethal in the first year of life. Due to its early lethality, little is known about bone dysplasia mechanism.
Aileen M. Barnes, Apratim Mitra, Marianne M. Knue, Alberta Derkyi, An Dang Do, Ryan K. Dale, Joan C. Marini   +6 more
doaj   +1 more source