Cell spreading on extracellular matrix proteins induces tyrosine phosphorylation of tensin
openalex +2 more sources
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
Cardiac function and extracellular matrix morphology are altered by chronic high fat diet in Drosophila larvae. [PDF]
Andrews RM+3 more
europepmc +1 more source
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs+17 more
wiley +1 more source
The effect of macromolecular crowders on deposition of extracellular matrix in astrocyte cultures. [PDF]
Nemati S+3 more
europepmc +1 more source
3D‐Printed Scaffolds Promote Enhanced Spinal Organoid Formation for Use in Spinal Cord Injury
3D‐printed organoid scaffolds with microscale channels are developed to enhance spinal cord injury recovery by guiding region‐specific spinal neural progenitor cells. These scaffolds promote axonal growth, cell maturation, and neuronal network formation.
Guebum Han+8 more
wiley +1 more source
Estrogen and Progesterone Exhibit Distinct Yet Coordinated Roles in the Regulation of Tendon Extracellular Matrix Remodeling. [PDF]
Sander AM, Connizzo BK.
europepmc +1 more source
Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo+8 more
wiley +1 more source
Liver Extracellular Matrix in Colorectal Liver Metastasis. [PDF]
Morabito M+7 more
europepmc +1 more source