Results 31 to 40 of about 192,244 (159)

Time-Resolved Extracellular Matrix Atlas of the Developing Human Skin Dermis

Frontiers in Cell and Developmental Biology, 2021
Skin aging is a physiological issue that is still relatively poorly understood. Studies have demonstrated that the dermal extracellular matrix (ECM) plays important roles in skin aging.
Mansheng Li, Xiao Li, Binghui Liu, Luye Lv, Wenjuan Wang, Dunqin Gao, Qiyu Zhang, Junyi Jiang, Mi Chai, Zhimin Yun, Yingxia Tan, Feng Gong, Zhihong Wu, Yunping Zhu, Yunping Zhu, Jie Ma, Ling Leng   +16 more
doaj   +1 more source

Matritecture: Mapping the extracellular matrix architecture during health and disease

Matrix Biology Plus, 2022
All cells in multicellular organisms are housed in the extracellular matrix (ECM), an acellular edifice built up by more than a thousand proteins and glycans.
Raphael Reuten, Alejandro E. Mayorca-Guiliani, Janine Terra Erler   +2 more
doaj   +1 more source

Extracellular matrix supports healing of transected rabbit Achilles tendon

Heliyon, 2018
Extracellular matrix (ECM) has been intensively used in cardio surgery. The main goal of this research was to determine if Achilles tendon healing could be promoted by applying extracellular matrix scaffold (CorMatrix®, USA). Sixteen (n = 16) New Zealand
Marija Lipar, Boris Zdilar, Mario Kreszinger, Marijana Ćorić, Berislav Radišić, Marko Samardžija, Rado Žic, Marko Pećin   +7 more
doaj   +1 more source

Fenofibrate attenuated glucose-induced mesangial cells proliferation and extracellular matrix synthesis via PI3K/AKT and ERK1/2. [PDF]

PLoS ONE, 2013
Excess mesangial extracellular matrix (ECM) and mesangial cell proliferation is the major pathologic feature of diabetic nephropathy (DN). Fenofibrate, a PPARα agonist, has been shown to attenuate extracellular matrix formation in diabetic nephropathy ...
Rui Zeng, Yan Xiong, Fengming Zhu, Zufu Ma, Wenhui Liao, Yong He, JinSeng He, Wei Li, Juan Yang, Qian Lu, Gang Xu, Ying Yao   +11 more
doaj   +1 more source

Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway

Frontiers in Cell and Developmental Biology, 2021
The positive role of macrophages in the osteogenesis of mesenchymal stem cells (MSCs) has been a recent research focus. On the other hand, MSCs could carefully regulate the paracrine molecules derived from macrophages.
Moyuan Deng, Jiulin Tan, Qijie Dai, Fei Luo, Jianzhong Xu   +4 more
doaj   +1 more source

Matrix metalloproteinase-induced cervical extracellular matrix remodelling in pregnancy and cervical cancer

Vascular Biology, 2022
The phenomenal extracellular matrix (ECM) remodelling of the cervix that precedes the myometrial contraction of labour at term or preterm appears to share some common mechanisms with the occurrence, growth, invasion and metastasis of cervical carcinoma ...
Emmanuel Amabebe, Henry Ogidi, Dilly O Anumba   +2 more
doaj   +1 more source

Extracellular Matrix Enzymes and Immune Cell Biology

Frontiers in Molecular Biosciences, 2021
Remodelling of the extracellular matrix (ECM) by ECM metalloproteinases is increasingly being associated with regulation of immune cell function. ECM metalloproteinases, including Matrix Metalloproteinases (MMPs), A Disintegrin and Metalloproteinases ...
Meagan McMahon, Siying Ye, Jess Pedrina, Daniel Dlugolenski, John Stambas   +4 more
doaj   +1 more source

Proteolytic Regulation of Synaptic Plasticity in the Mouse Primary Visual Cortex: Analysis of Matrix Metalloproteinase 9 Deficient Mice.

Frontiers in Cellular Neuroscience, 2015
The extracellular matrix (ECM) is known to play important roles in regulating neuronal recovery from injury. The ECM can also impact physiological synaptic plasticity, although this process is less well understood.
Emily A Kelly, Amanda S Russo, Cory D Jackson, Cassandra E Lamantia, Ania K Majewska   +4 more
doaj   +1 more source

ELFN1 is a new extracellular matrix (ECM)-associated protein

Life Sciences
The ELFN1, discovered in 2007, is a single-pass transmembrane protein. Studies conducted thus far to elucidate the function of the Elfn1 have been limited only to animal studies. These studies have reported that ELFN1 is a universal binding partner of metabotropic glutamate receptors (mGluRs) in the central nervous system and its functional deficiency ...
Selda Ayhan, Ali Dursun
openaire   +3 more sources

Red Wine administration to Apolipoprotein E-deficient Mice reduces their Macrophage-derived Extracellular Matrix Atherogenic Properties

Biological Research, 2004
Proteoglycans (PGs) from the arterial extracellular matrix (ECM) contribute to the trapping of LDL and oxidized LDL (Ox-LDL) in the arterial wall, a phenomenon called "lipoprotein retention".
MARIELLE KAPLAN, MICHAEL AVIRAM
doaj