Results 21 to 30 of about 2,138,893 (293)

Human extracellular matrix (ECM)-like collagen and its bioactivity. [PDF]

Regen Biomater
Abstract Collagen, the most abundant structural protein in the human extracellular matrix (ECM), provides essential support for tissues and guides tissue development. Despite its widespread use in tissue engineering, there remains uncertainty regarding the optimal selection of collagen sources. Animal-derived sources pose challenges such
Zhou H, Li W, Pan L, Zhu T, Zhou T, Xiao E, Wei Q.   +6 more
europepmc   +3 more sources

The Repertoire of Tissue Inhibitors of Metalloproteases: Evolution, Regulation of Extracellular Matrix Proteolysis, Engineering and Therapeutic Challenges

Life, 2022
Tissue inhibitors of metalloproteases (TIMPs) belong to a fascinating protein family expressed in all Metazoa. They act as regulators of the turnover of the extracellular matrix, and they are consistently involved in essential processes.
Salvatore Costa, Maria Antonietta Ragusa, Gabriele Lo Buglio, Simone Dario Scilabra, Aldo Nicosia   +4 more
doaj   +1 more source

Osteopontin and fibronectin levels are decreased in vitreous of autoimmune uveitis and retinal expression of both proteins indicates ECM re-modeling. [PDF]

, 2011
Autoimmune uveitis is an intraocular inflammation that arises through autoreactive T-cells attacking the inner eye, eventually leading to blindness. However, the contributing molecular pathomechanisms within the affected tissues remain as yet elusive ...
Cornelia A. Deeg, Amann, B., Amann, Barbara, Hofmaier, F., Eberhardt Christina, Hauck Stefanie M., Barbara Amann, Hofmaier Florian, Christina Eberhardt, Florian Hofmaier, Eberhardt, Christina, Hauck, S.M., Cornelia A Deeg, Deeg Cornelia A., Amann Barbara, Stefanie M Hauck, Stefanie M. Hauck, Deeg, Cornelia A., Hauck, Stefanie M., Eberhardt, C., Hofmaier, Florian, Deeg, C.A.   +21 more
core   +2 more sources

3D mapping of native extracellular matrix reveals cellular responses to the microenvironment

Journal of Structural Biology: X, 2019
Cells and extracellular matrix (ECM) are mutually interdependent: cells guide self-assembly of ECM precursors, and the resulting ECM architecture supports and instructs cells.
Zipora Lansky, Yael Mutsafi, Lothar Houben, Tal Ilani, Gad Armony, Sharon G. Wolf, Deborah Fass   +6 more
doaj   +1 more source

Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach. [PDF]

, 2011
Abdominal aortic aneurysms (AAA) are characterized by pathological remodeling of the aortic extracellular matrix (ECM). However, besides the well-characterized elastolysis and collagenolysis little is known about changes in other ECM proteins.
Mandal, K, Marjan Jahangiri, Didangelos, Athanasios, Didangelos, A, Smith, A, Mandal, Kaushik, Saje, A, Smith, Alberto, Xu, Q, Jahangiri, M, Mayr, Manuel; id_orcid, Mayr, M, Athanasios Didangelos, Alberto Smith, Qingbo Xu, Jahangiri, Marjan, Kaushik Mandal, Angelika Saje, Saje, Angelika, Yin, Xiaoke; id_orcid, Xu, Qingbo, Xiaoke Yin, Manuel Mayr, Yin, X   +23 more
core   +1 more source

Production and degradation of extracellular matrix in reversible glomerular lesions in rat model of habu snake venom-induced glomerulonephritis [PDF]

, 2012
We investigated the mechanism of development and repair process of glomerular injury in a rat model of habu snake (Trimeresurus flavoviridis) venom (HSV)-induced glomerulonephritis. Glomerulonephritis was induced in rats by intravenously injecting HSV at
Miyazaki, Masanobu, Nishino, Tomoya, Furusu, Akira, Kohno, Shigeru, Abe, Katsushige, Koji, Takehiko, Obata, Yoko, Kawazu, Tayo   +7 more
core   +1 more source

Cellular responses to dental extracellular matrix molecules [PDF]

, 2012
Dental pulp contains mesenchymal stem cells (MSCs) similar to those present within bone marrow. Several factors are postulated to contribute to the signalling involved in regulating these cells.
Smith, James George William
core   +7 more sources

Imaging the Extracellular Matrix in Prevalent Cardiovascular Diseases

Applied Sciences, 2020
The extracellular matrix (ECM) is a highly complex macromolecular network present in all tissues and organs. The ECM is continuously remodelling under an orchestrated process facilitated by many matrix-degrading and matrix-synthesising enzymes in both ...
Nadia Chaher, Reza Hajhosseiny, Alkystis Phinikaridou, René M. Botnar   +3 more
doaj   +1 more source

Escherichia coli Biofilms Have an Organized and Complex Extracellular Matrix Structure

mBio, 2013
Bacterial biofilms are ubiquitous in nature, and their resilience is derived in part from a complex extracellular matrix that can be tailored to meet environmental demands.
Chia Hung, Yizhou Zhou, Jerome S. Pinkner, Karen W. Dodson, Jan R. Crowley, John Heuser, Matthew R. Chapman, Maria Hadjifrangiskou, Jeffrey P. Henderson, Scott J. Hultgren   +9 more
doaj   +1 more source

Extracellular matrix dynamics: tracking in biological systems and their implications

Journal of Biological Engineering, 2022
The extracellular matrix (ECM) constitutes the main acellular microenvironment of cells in almost all tissues and organs. The ECM not only provides mechanical support, but also mediates numerous biochemical interactions to guide cell survival ...
Michael Hu, Zihan Ling, Xi Ren
doaj   +1 more source