Results 1 to 10 of about 200,616 (156)

The Role of the Extracellular Matrix (ECM) in Wound Healing: A Review [PDF]

open access: yesBiomimetics, 2022
The extracellular matrix (ECM) is a 3-dimensional structure and an essential component in all human tissues. It is comprised of varying proteins, including collagens, elastin, and smaller quantities of structural proteins. Studies have demonstrated the ECM aids in cellular adherence, tissue anchoring, cellular signaling, and recruitment of cells ...
Robert B Diller
exaly   +5 more sources

Heparanase: A Multitasking Protein Involved in Extracellular Matrix (ECM) Remodeling and Intracellular Events [PDF]

open access: yesCells, 2018
Heparanase (HPSE) has been defined as a multitasking protein that exhibits a peculiar enzymatic activity towards HS chains but which simultaneously performs other non-enzymatic functions.
Valentina Masola   +3 more
doaj   +4 more sources

The Role of Extracellular Matrix (ECM) Adhesion Motifs in Functionalised Hydrogels. [PDF]

open access: yesMolecules, 2023
To create functional tissue engineering scaffolds, biomaterials should mimic the native extracellular matrix of the tissue to be regenerated. Simultaneously, the survival and functionality of stem cells should also be enhanced to promote tissue organisation and repair.
Morwood AJ   +3 more
europepmc   +6 more sources

Extracellular Matrix (ECM) and Fibrosis in Adipose Tissue: Overview and Perspectives. [PDF]

open access: yesCompr Physiol, 2023
Abstract Fibrosis in adipose tissue is a major driver of obesity‐related metabolic dysregulation. It is characterized by an overaccumulation of extracellular matrix (ECM) during unhealthy expansion of adipose tissue in response to over nutrition.
Sun K, Li X, Scherer PE.
europepmc   +3 more sources

Human extracellular matrix (ECM)-like collagen and its bioactivity. [PDF]

open access: yesRegen Biomater
Abstract Collagen, the most abundant structural protein in the human extracellular matrix (ECM), provides essential support for tissues and guides tissue development. Despite its widespread use in tissue engineering, there remains uncertainty regarding the optimal selection of collagen sources. Animal-derived sources pose challenges such
Zhou H   +6 more
europepmc   +3 more sources

Extracellular Matrix (ECM) [PDF]

open access: yes, 2012
The region of space at the periphery of cyanobacterial cells is the interface between the environment and intracellular processes. This metaspace may include a structure appressed to the outer wall and membrane, such as an extracellular polysaccharide (EPS), a structural and/or physiological discontinuity in the control of flow metabolites, as well as ...
Helm R.F., Potts M.
  +8 more sources

Development potential of extracellular matrix hydrogels as hemostatic materials

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
The entry of subcutaneous extracellular matrix proteins into the circulation is a key step in hemostasis initiation after vascular injury. However, in cases of severe trauma, extracellular matrix proteins are unable to cover the wound, making it ...
Dan Cai, Wei Weng
doaj   +1 more source

Extracellular Vesicles as Regulators of the Extracellular Matrix

open access: yesBioengineering, 2023
Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids, proteins, and lipids to facilitate cell-to-cell communication.
Neil J. Patel   +2 more
doaj   +1 more source

The extracellular matrix of dystrophic mouse diaphragm accounts for the majority of its passive stiffness and is resistant to collagenase digestion

open access: yesMatrix Biology Plus, 2023
The healthy skeletal muscle extracellular matrix (ECM) has several functions including providing structural integrity to myofibers, enabling lateral force transmission, and contributing to overall passive mechanical properties.
Ross P. Wohlgemuth   +5 more
doaj   +1 more source

Interplay between Extracellular Matrix and Neutrophils in Diseases

open access: yesJournal of Immunology Research, 2021
The extracellular matrix (ECM) is a highly dynamic and complex network structure, which exists in almost all tissues and is the microenvironment that cells rely on for survival.
Yanyan Zhu   +6 more
doaj   +1 more source

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