Results 31 to 40 of about 2,138,893 (293)
Extracellular matrix guidance of autophagy: a mechanism regulating cancer growth
Open Biology, 2022 The extracellular matrix (ECM) exists as a dynamic network of biophysical and biochemical factors that maintain tissue homeostasis. Given its sensitivity to changes in the intra- and extracellular space, the plasticity of the ECM can be pathological in ...
Carolyn G. Chen, Renato V. Iozzo
doaj +1 more source
Thrombospondin-4, an extracellular matrix protein expressed in the developing and adult nervous system promotes neurite outgrowth [PDF]
, 1995 Extracellular matrix (ECM) molecules are involved in multiple aspects of cell-to-cell signaling during development and in the adult. In nervous system development, specific recognition processes, e.g., during axonal pathfinding and synaptogenesis involve
Arber, S., P Caroni, S Arber, Caroni, P.
core +1 more source
Extracellular Matrix Recycling as a Novel Plasticity Mechanism With a Potential Role in Disease
, 2022 The extracellular matrix (ECM) stabilizes neural circuits and synapses in the healthy brain, while also retaining the ability to be remodeled, to allow synapses to be plastic.
Rizzoli, Silvio O.; 1Institute of Neuro- and Sensory Physiology, University Medical Center Göttingen, Göttingen, Germany +3 more
core +1 more source
Mathematics, 2020 Extracellular matrix (ECM) proteins play an important role in a series of biological processes of cells. The study of ECM proteins is helpful to further comprehend their biological functions.
Minghui Wang +6 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Pulmonary arterial hypertension has characteristic changes to the mechanical environment, extracellular matrix, and cellular proliferation. In order to develop a culture system to investigate extracellular matrix (ECM) compositional-dependent changes in ...
Patrick A. Link +2 more
doaj +1 more source
Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer [PDF]
Reproductive Biology and Endocrinology, 2004 Prostate cancer (PCa) is no exception to the multi-step process of metastasis. As PCa progresses, changes occur within the microenvironments of both the malignant cells and their targeted site of metastasis, enabling the necessary responses that result in successful translocation.
Sikes Robert A +2 more
openaire +3 more sources
Extracellular Matrix Proteases - Cytokine Regulation Role in Cancer and Pregnancy
, 2010 The extracellular matrix proteases act in diverse physiological and pathological processes involving tumor growth, angiogenesis, and pregnancy through the cleavage of extracellular matrix (ECM) and non-matrix proteinaceous substrates.
許博欽;張文君;王鵬惠;林世明;黃思誠 +1 more
core +1 more source
Bursting Dynamics of Spiking Neural Network Induced by Active Extracellular Medium
Mathematics, 2023 We propose a mathematical model of a spiking neural network (SNN) that interacts with an active extracellular field formed by the brain extracellular matrix (ECM). The SNN exhibits irregular spiking dynamics induced by a constant noise drive.
Sergey V. Stasenko, Victor B. Kazantsev
doaj +1 more source
The Extracellular Matrix, the Silent ‘Architect’ of Glioma
BiomedicinesThe brain’s extracellular matrix (ECM) serves as a dynamic and instructive regulator of glioma progression. The ECM provides structural support while integrating pharmacological and mechanical signals that influence glioma initiation, progression, and ...
Carmen Rubio +5 more
doaj +1 more source
Extracellular matrix supports healing of transected rabbit Achilles tendon
Heliyon, 2018 Extracellular matrix (ECM) has been intensively used in cardio surgery. The main goal of this research was to determine if Achilles tendon healing could be promoted by applying extracellular matrix scaffold (CorMatrix®, USA). Sixteen (n = 16) New Zealand
Marija Lipar +7 more
doaj +1 more source