Results 91 to 100 of about 565,976 (302)

Aggregation substance-mediated adherence of Enterococcus faecalis to immobilized extracellular matrix proteins

, 2001
Aggregation substance (AS) of Enterococcus faecalis (E. faecalis), a sex pheromone plasmid encoded cell surface protein, mediates the formation of bacterial aggregates, thereby promoting plasmid transfer.
Muscholl-Silberhorn, Albrecht, Wirth, Reinhard, Rozdzinski, Eva, Susa, Milorad, Marre, Reinhard   +4 more
core   +1 more source

An immunofluorescence study on VEGF and extracellular matrix proteins in human periodontal ligament during tooth movement

, 2019
The periodontal ligament (PDL) is a highly vascularized connective tissue surrounding the root of a tooth. In particular, the PDL is continuously exposed to mechanical stresses during the phases of mastication, and it provides physical, sensory, and ...
Cutroneo G., Nicita F., Bramanti A., Di Mauro D., Matarese G., Lauritano F., Rizzo G., Cervino G., Favaloro A., Centofanti A., Militi A.   +10 more
core   +1 more source

A Biofilm Matrix-Associated Protease Inhibitor Protects Pseudomonas aeruginosa from Proteolytic Attack

mBio, 2018
Pseudomonas aeruginosa produces an extracellular biofilm matrix that consists of nucleic acids, exopolysaccharides, lipid vesicles, and proteins. In general, the protein component of the biofilm matrix is poorly defined and understudied relative to the ...
Boo Shan Tseng, Courtney Reichhardt, Gennifer E. Merrihew, Sophia A. Araujo-Hernandez, Joe J. Harrison, Michael J. MacCoss, Matthew R. Parsek   +6 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Top 25 extracellular matrix proteins, top 25 membrane proteins, and top six growth factors and cytokines in perifascial areolar tissue.

Top 25 extracellular matrix proteins, top 25 membrane proteins, and top six growth factors and cytokines in perifascial areolar tissue.
Yasuo Yoshitomi (17996336), Toru Miyanaga (17996333), Aiko Miyanaga (17996339)   +2 more
core   +1 more source

Extracellular matrix proteins identified in wound exudates collected from mice at 1, 6 and 24 h after injection of B. asper venom.

, 2016
Extracellular matrix proteins identified in wound exudates collected from mice at 1, 6 and 24 h after injection of B. asper venom.
Alexandra Rucavado (32147), Cristina Herrera (576490), Jéssica Kele A. Macêdo (729670), Andrés Feoli (2585824), Jay W. Fox (164576), Teresa Escalante (337914), José María Gutiérrez (62868)   +6 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Extracellular matrix proteins identified in wound exudate collected from mice injected with PI, PII or PIII SVMPs.

, 2015
Values in bold and underlined correspond to proteins for which at least one SVMP induced an increment of at least three times as compared to another SVMP.Extracellular matrix proteins identified in wound exudate collected from mice injected with PI, PII ...
Alexandra Rucavado (32147), Cristina Herrera (576490), Jéssica Kele A. Macêdo (729670), Jay W. Fox (164576), Diego Morazán (729669), Teresa Escalante (337914), Mathieu-Benoit Voisin (729668), José María Gutiérrez (62868), Libia Sanz (144843), Juan J. Calvete (144840), Sussan Nourshargh (157725)   +10 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source