This study presents a custom‐made soft pneumatic device (SPD) that mimics complex mechanical forces and fluid flow to enhance in vitro cell differentiation. It shows that low mechanotransduction promotes MSC differentiation into osteoprogenitor cells, while high mechanotransduction causes structural disruptions and cell detachment, providing new ...
Gwang‐Bum Im+9 more
wiley +1 more source
Expression of intramuscular extracellular matrix proteins in vastus lateralis muscle fibres between atrophic and non-atrophic COPD. [PDF]
Kritikaki E+4 more
europepmc +1 more source
Advanced Glycosylation End Products Up-Regulate Connective Tissue Growth Factor (Insulin-Like Growth Factor-Binding Protein-Related Protein 2) in Human Fibroblasts: A Potential Mechanism for Expansion of Extracellular Matrix in Diabetes Mellitus [PDF]
Stephen M. Twigg
openalex +1 more source
This study reports a novel strategy for preparing a biocompatible adhesive hydrogel crosslinked with a muscle tissue‐derived extracellular matrix (MEM) for in situ muscle regeneration. As a natural crosslinker, MEM not only mediates combinatorial polymer networks but also stimulates satellite cells to induce a cell‐free therapeutic solution.
Eun Je Jeon+6 more
wiley +1 more source
The role of human extracellular matrix proteins in defining Staphylococcus aureus biofilm infections. [PDF]
Bhattacharya M, Horswill AR.
europepmc +1 more source
Characterization of EHD4, an EH Domain-containing Protein Expressed in the Extracellular Matrix [PDF]
Huey‐Ju Kuo+4 more
openalex +1 more source
This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim+8 more
wiley +1 more source
Fibrosis and expression of extracellular matrix proteins in human interventricular septum in aortic valve stenosis and regurgitation. [PDF]
Sedmera D+8 more
europepmc +1 more source
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang+14 more
wiley +1 more source
Enhancing the Cardiogenic Potential of Human Mesenchymal Stem Cells via Extracellular Matrix Proteins. [PDF]
Chizhikova G, Khotin M, Bildyug N.
europepmc +1 more source