Results 51 to 60 of about 565,976 (302)

Well preserved non-collagenous extracellular matrix proteins in ancient human bone and teeth

open access: yes, 2007
Ancient bones in a good preservation state, ascertained by microscopic techniques, conserve extracellular matrix proteins over thousands of years. With new techniques, intact extracellular matrix proteins from ancient bones and teeth are extracted and ...
Schmidt-Schultz, Tyede Helen   +3 more
core   +1 more source

Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm

open access: yesExperimental and Molecular Medicine, 2019
Aortic aneurysm: Different locations, different causes A review of aneurysm formation, swelling in blood vessel, in the aorta, examines distinctions between two forms of the condition and the role of proteins in the extracellular matrix which surrounds ...
Sayantan Jana   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Carbon nanotube interaction with extracellular matrix proteins producing scaffolds for tissue engineering

open access: yesInternational Journal of Nanomedicine, 2012
Fernanda MP Tonelli,1 Anderson K Santos,1 Katia N Gomes,2 Eudes Lorençon,2 Silvia Guatimosim,3 Luiz O Ladeira,2 Rodrigo R Resende11Cell Signaling and Nanobiotechnology Laboratory, Department of Biochemistry and Immunology, Federal University ...
Tonelli FM   +6 more
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

PROTEOMIC COMPARISON OF EXTRACELLULAR MATRIX WITHIN LIVER METASTASES OF COLORECTAL CANCER AND NORMAL LIVER

open access: yesФундаментальная и клиническая медицина, 2018
Aim. To investigate the composition of extracellular matrix proteins in colorectal cancer liver metastases and normal liver. Materials and Methods.
ARSENIY E. Yuzhalin, RUTH J. Muschel
doaj  

Biochemical and biomechanical properties of the pacemaking sinoatrial node extracellular matrix are distinct from contractile left ventricular matrix. [PDF]

open access: yesPLoS ONE, 2017
Extracellular matrix plays a role in differentiation and phenotype development of its resident cells. Although cardiac extracellular matrix from the contractile tissues has been studied and utilized in tissue engineering, extracellular matrix properties ...
Jessica M Gluck   +8 more
doaj   +1 more source

Focusing on the Native Matrix Proteins in Calcific Aortic Valve Stenosis

open access: yesJACC: Basic to Translational Science, 2023
Summary: Calcific aortic valve stenosis (CAVS) is a widespread valvular heart disease affecting people in aging societies, primarily characterized by fibrosis, inflammation, and progressive calcification, leading to valve orifice stenosis.
Nikolaos Anousakis-Vlachochristou, MD   +3 more
doaj   +1 more source

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