Cell surface localization of tissue transglutaminase is dependent on a fibronectin-binding site in its N-terminal beta-sandwich domain [PDF]
Increasing evidence indicates that tissue transglutaminase (tTG) plays a role in the assembly and remodeling of extracellular matrices and promotes cell adhesion.
Aeschlimann, D +5 more
core +1 more source
Biofilm formation by Staphylococcus aureus involves the formation of an extracellular matrix, but the composition of this matrix has been uncertain. Here we report that the matrix is largely composed of cytoplasmic proteins that reversibly associate with
Lucy Foulston +3 more
doaj +1 more source
Stepwise Evolution of Coral Biomineralization Revealed with Genome-Wide Proteomics and Transcriptomics. [PDF]
Despite the importance of stony corals in many research fields related to global issues, such as marine ecology, climate change, paleoclimatogy, and metazoan evolution, very little is known about the evolutionary origin of coral skeleton formation.
Takeshi Takeuchi +4 more
doaj +1 more source
A secretory kinase complex regulates extracellular protein phosphorylation. [PDF]
Although numerous extracellular phosphoproteins have been identified, the protein kinases within the secretory pathway have only recently been discovered, and their regulation is virtually unexplored.
Cui, Jixin +5 more
core +2 more sources
Extracellular matrix proteins involved in pseudoislets formation [PDF]
Extracellular matrix proteins are known to mediate, through integrins, cell adhesion and are involved in a number of cellular processes, including insulin expression and secretion in pancreatic islets. We investigated whether expression of some extracellular matrix proteins were implied in islets-like structure formation, named pseudoislets.
Maillard, Elisa +6 more
openaire +2 more sources
A view of the genetic and proteomic profile of extracellular matrix molecules in aging and stroke
IntroductionModification of the extracellular matrix (ECM) is one of the major processes in the pathology of brain damage following an ischemic stroke.
Martina Chmelova +10 more
doaj +1 more source
Association of 2 Lysyl Oxidase Gene Single Nucleotide Polymorphisms with Keratoconus
Purpose: Keratoconus (KC) is the most common primary ectatic corneal disease, characterized by progressive thinning of the cornea, affecting its shape and structure and leading to visual loss.
Sana Niazi, MD +7 more
doaj +1 more source
Congenital Disorders of Deficiency in Glycosaminoglycan Biosynthesis
Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, and heparan sulfate are covalently attached to specific core proteins to form proteoglycans, which are distributed at the cell surface as well as in the extracellular matrix ...
Shuji Mizumoto, Shuhei Yamada
doaj +1 more source
Importance of geometry of the extracellular matrix in endochondral bone differentiation. [PDF]
Subcutaneous implantation of coarse powders (74-420 micron) of demineralized diaphyseal bone matrix resulted in the local differentiation of endochondral bone.
Reddi, AH, Sampath, TK
core +1 more source
The basement membrane protein nidogen-1 supports platelet adhesion and activation
The core structure of the extracellular basement membrane is made up of self-assembling networks of collagen and laminin which associate with each other through the bridging adapter proteins including the sulfated monomeric glycoprotein nidogen.
Hari Hara Sudhan Lakshmanan +12 more
doaj +1 more source

