Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell- and nano-scale process extension for neural repair applications. [PDF]
The extracellular matrix plays a critical role in modulating cell behaviour in the developing and adult central nervous system influencing neural cell morphology, function and growth.
O'Connor C +9 more
europepmc +2 more sources
Interaction of Extracellular Matrix Protein 1 with Extracellular Matrix Components: ECM1 Is a Basement Membrane Protein of the Skin [PDF]
The extracellular matrix protein 1 (ECM1) is a secreted glycoprotein, which plays an important role in the structural and functional biology of the skin as demonstrated by the identification of loss-of-function mutations in ECM1 as cause of the genodermatosis lipoid proteinosis, characterized by reduplication of the skin basement membrane and ...
Sercu, Sandy +8 more
openaire +3 more sources
The effects and mechanisms of extracellular matrix proteins on congenital tooth malformation
Congenital tooth developmental anomalies refer to a type of tooth disease where the shape or structure of the teeth is abnormal during embryonic development or after birth.
Fan Zhipeng, Yang Haoqing
core +1 more source
A view of the genetic and proteomic profile of extracellular matrix molecules in aging and stroke
IntroductionModification of the extracellular matrix (ECM) is one of the major processes in the pathology of brain damage following an ischemic stroke.
Martina Chmelova +10 more
doaj +1 more source
Stepwise Evolution of Coral Biomineralization Revealed with Genome-Wide Proteomics and Transcriptomics. [PDF]
Despite the importance of stony corals in many research fields related to global issues, such as marine ecology, climate change, paleoclimatogy, and metazoan evolution, very little is known about the evolutionary origin of coral skeleton formation.
Takeshi Takeuchi +4 more
doaj +1 more source
The matrilins – adaptor proteins in the extracellular matrix
The matrilins form a four‐member family of modular, multisubunit matrix proteins, which are expressed in cartilage but also in many other forms of extracellular matrix. They participate in the formation of fibrillar or filamentous structures and are often associated with collagens.
Wagener, Raimund +6 more
openaire +2 more sources
The basement membrane protein nidogen-1 supports platelet adhesion and activation
The core structure of the extracellular basement membrane is made up of self-assembling networks of collagen and laminin which associate with each other through the bridging adapter proteins including the sulfated monomeric glycoprotein nidogen.
Hari Hara Sudhan Lakshmanan +12 more
doaj +1 more source
N-terminal specific conjugation of extracellular matrix proteins to 2-pyridinecarboxaldehyde functionalized polyacrylamide hydrogels. [PDF]
Polyacrylamide hydrogels have been used extensively to study cell responses to the mechanical and biochemical properties of extracellular matrix substrates.
Kumar, Sanjay +4 more
core +1 more source
Association of 2 Lysyl Oxidase Gene Single Nucleotide Polymorphisms with Keratoconus
Purpose: Keratoconus (KC) is the most common primary ectatic corneal disease, characterized by progressive thinning of the cornea, affecting its shape and structure and leading to visual loss.
Sana Niazi, MD +7 more
doaj +1 more source
Extracellular Matrix Proteins and Tumor Angiogenesis
Tumor development is a complex process that relies on interaction and communication between a number of cellular compartments. Much of the mass of a solid tumor is comprised of the stroma which is richly invested with extracellular matrix. Within this matrix are a host of matricellular proteins that regulate the expression and function of a myriad of ...
Campbell, N. E. +5 more
openaire +3 more sources

