Results 11 to 20 of about 5,777,110 (367)
Current Techniques for Investigating the Brain Extracellular Space [PDF]
Frontiers in Neuroscience, 2020 The brain extracellular space (ECS) is a continuous reticular compartment that lies between the cells of the brain. It is vast in extent relative to its resident cells, yet, at the same time the nano- to micrometer dimensions of its channels and ...
Federico N. Soria +6 more
doaj +7 more sources
Local diffusion in the extracellular space of the brain
Neurobiology of Disease, 2023 The brain extracellular space (ECS) is a vast interstitial reticulum of extreme morphological complexity, composed of narrow gaps separated by local expansions, enabling interconnected highways between neural cells.
Jan Tønnesen +2 more
doaj +5 more sources
Protein Dynamics in the Plant Extracellular Space [PDF]
Proteomes, 2016 The extracellular space (ECS or apoplast) is the plant cell compartment external to the plasma membrane, which includes the cell walls, the intercellular space and the apoplastic fluid (APF).
Leonor Guerra-Guimarães +4 more
doaj +5 more sources
Diffusion in Brain Extracellular Space [PDF]
Physiological Reviews, 2008 Diffusion in the extracellular space (ECS) of the brain is constrained by the volume fraction and the tortuosity and a modified diffusion equation represents the transport behavior of many molecules in the brain. Deviations from the equation reveal loss of molecules across the blood-brain barrier, through cellular uptake, binding, or other mechanisms ...
Eva Syková, Charles Nicholson
semanticscholar +5 more sources
Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling [PDF]
Nature Communications, 2020 The nanoscale organisation of the brain extracellular space can be studied in vivo. Here, the authors investigate how it changes in response to α-synuclein pathology, and identify interactions between microglia and the extracellular matrix.
Federico N. Soria +11 more
doaj +3 more sources
Diffusion in the extracellular space in brain and tumors [PDF]
Physical Biology, 2013 Diffusion of solutes and macromolecules in the extracellular space (ECS) in brain is important for non-synaptic intercellular communication, extracellular ionic buffering, and delivery of drugs and metabolites. Diffusion in tumor ECS is important for delivery of anti-tumor drugs.
A. S. Verkman
semanticscholar +7 more sources
Potential of extracellular space for tissue regeneration in dentistry [PDF]
Frontiers in Physiology, 2022 With the proven relationship between oral and general health and the growing aging population, it is pivotal to provide accessible therapeutic approaches to regenerate oral tissues and restore clinical function.
Anahid A. Birjandi, Paul Sharpe
doaj +2 more sources
Microglia as hackers of the matrix: sculpting synapses and the extracellular space. [PDF]
Cell Mol Immunol, 2021 Microglia shape the synaptic environment in health and disease, but synapses do not exist in a vacuum. Instead, pre- and postsynaptic terminals are surrounded by extracellular matrix (ECM), which together with glia comprise the four elements of the ...
Crapser JD +3 more
europepmc +2 more sources
Near-Infrared Carbon Nanotube Tracking Reveals the Nanoscale Extracellular Space around Synapses. [PDF]
Nano Lett, 2022 We provide evidence of a local synaptic nano-environment in the brain extracellular space (ECS) lying within 500 nm of postsynaptic densities. To reveal this brain compartment, we developed a correlative imaging approach dedicated to thick brain tissue ...
Paviolo C +7 more
europepmc +2 more sources
Mechanism of extracellular space changes in cryptococcal brain granuloma revealed by MRI tracer [PDF]
Frontiers in Neuroscience, 2022 PurposeThis study aimed to investigate the changes in extracellular space (ECS) in cryptococcal brain granuloma and its pathological mechanism.Materials and methodsThe animal model of cryptococcal brain granuloma was established by injecting 1 × 106 CFU ...
Nuerbiyemu Abulikemu +25 more
doaj +2 more sources