Results 11 to 20 of about 247,522 (191)

Demonstration of extracellular space by freeze-drying in the cerebellar molecular layer [PDF]

open access: bronze, 1966
In electron micrographs of the molecular layer of the mouse cerebellum frozen within 30 sec of circulatory arrest and subsequently dried at -79 °C an appreciable extracellular space was found between the axons of the granular cells.
A. Van Harreveld, S. K. Malhotra
openalex   +4 more sources

Potential of extracellular space for tissue regeneration in dentistry

open access: yesFrontiers in Physiology, 2022
With the proven relationship between oral and general health and the growing aging population, it is pivotal to provide accessible therapeutic approaches to regenerate oral tissues and restore clinical function.
Anahid A. Birjandi, Paul Sharpe
doaj   +1 more source

New Insights into Alzheimer’s Disease: Novel Pathogenesis, Drug Target and Delivery

open access: yesPharmaceutics, 2023
Alzheimer’s disease (AD), the most common type of dementia, is characterized by senile plaques composed of amyloid β protein (Aβ) and neurofilament tangles derived from the hyperphosphorylation of tau protein.
Haishu Chen   +7 more
doaj   +1 more source

Unconventional Pathways of Protein Secretion: Mammals vs. Plants

open access: yesFrontiers in Cell and Developmental Biology, 2022
In eukaryotes, many proteins contain an N-terminal signal peptide that allows their translocation into the endoplasmic reticulum followed by secretion outside the cell according to the classical secretory system. However, an increasing number of secreted
Elisa Maricchiolo   +5 more
doaj   +1 more source

Extracellular volume fraction using contrast-enhanced CT is useful in differentiating intrahepatic cholangiocellular carcinoma from hepatocellular carcinoma

open access: yesFrontiers in Oncology, 2023
ObjectivesTo evaluate whether tumor extracellular volume fraction (fECV) on contrast-enhanced computed tomography (CT) aids in the differentiation between intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC).MethodsIn this ...
T. Honda   +12 more
doaj   +1 more source

What Triggers the Interictal Epileptic Spike? A Multimodal Multiscale Analysis of the Dynamic of Synaptic and Non-synaptic Neuronal and Vascular Compartments Using Electrical and Optical Measurements

open access: yesFrontiers in Neurology, 2021
Interictal spikes (IISs) may result from a disturbance of the intimate functional balance between various neuronal (synaptic and non-synaptic), vascular, and metabolic compartments.
Cristian Arnal-Real   +4 more
doaj   +1 more source

Mechanism of extracellular space changes in cryptococcal brain granuloma revealed by MRI tracer

open access: yesFrontiers in Neuroscience, 2022
PurposeThis study aimed to investigate the changes in extracellular space (ECS) in cryptococcal brain granuloma and its pathological mechanism.Materials and methodsThe animal model of cryptococcal brain granuloma was established by injecting 1 × 106 CFU ...
Nuerbiyemu Abulikemu   +25 more
doaj   +1 more source

Proteome readjustments in the apoplastic space of Arabidopsis thaliana ggt1 mutant leaves exposed to UV-B radiation [PDF]

open access: yes, 2015
Ultraviolet-B radiation acts as an environmental stimulus, but in high doses it has detrimental effects on plant metabolism. Plasma membranes represent a major target for ROS generated by this harmful radiation.
ARRIGONI, GIORGIO   +8 more
core   +2 more sources

A space-fractional cable equation for the propagation of action potentials in myelinated neurons [PDF]

open access: yes, 2020
Myelinated neurons are characterized by the presence of myelin, a multilaminated wrapping around the axons formed by specialized neuroglial cells. Myelin acts as an electrical insulator and therefore, in myelinated neurons, the action potentials do not ...
Drapaca, Corina S.   +2 more
core   +2 more sources

Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

open access: yeseLife, 2017
Transport of solutes through brain involves diffusion and convection. The importance of convective flow in the subarachnoid and paravascular spaces has long been recognized; a recently proposed ‘glymphatic’ clearance mechanism additionally suggests that ...
Alex J Smith   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy