Advanced Healthcare Materials, EarlyView.A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang +9 more
wiley +1 more source
Introduction: dialogue with invaders from extracellular space
, 2000 Guy Tran Van Nhieu, David M. Ojcius
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Random-Walk Model of Diffusion in Three Dimensions in Brain Extracellular Space: Comparison with Microfiberoptic Photobleaching Measurements [PDF]
, 2008 Songwan Jin, Zsolt Zádor, A.S. Verkman
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Autophagy and Exocytosis of Lipofuscin Into the Basolateral Extracellular Space of Human Retinal Pigment Epithelium From Fetal Development to Adolescence. [PDF]
Invest Ophthalmol Vis SciShahhossein-Dastjerdi S +4 more
europepmc +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Chronic alcohol consumption alters extracellular space geometry and transmitter diffusion in the brain. [PDF]
Sci Adv, 2020 De Santis S +14 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Rod‐shaped particles outperform spherical particles of the same volume in preventing neutrophil infiltration to inflamed areas, both in vitro and in vivo. This therapeutic effectiveness is attributed to better cell targeting and decreased cell motility, resulting from the geometry‐driven phagocytosis and inhibited actin polymerization.
M. Valentina Guevara +7 more
wiley +1 more source
In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate [PDF]
, 2008 Rick F. Thorne +3 more
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Advanced Healthcare Materials, EarlyView.This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide +7 more
wiley +1 more source
Microfiberoptic Measurement of Extracellular Space Volume in Brain and Tumor Slices Based on Fluorescent Dye Partitioning [PDF]
, 2010 Hua Zhang, A. S. Verkman
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