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Advanced Healthcare Materials, EarlyView.A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues +6 more
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Editorial: Brain Extracellular Space: Geometry, Matrix and Physiological Importance
Basic and Clinical Neuroscience, 2013 Padideh Kamali-Zare, Charles Nicholson
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Selective Radioprotection in Extracellular Space
Radiology, 1974Most radioprotective agents are not discriminatory as they can protect both tumor and healthy tissue. The effects of radioprotective agents on radiation-induced free radicals in the extracellular ground substance were investigated by ESR spectroscopy.
R A, Peckauskas, M, Rotman, I, Pullman
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Alarmins of the extracellular space
Seminars in Immunology, 2018The ability of the immune system to discriminate between healthy-self, abnormal-self, and non-self has been attributed mainly to alarmins signaling as "danger signals". It is now evident, however, that alarmins are much more complex and can perform specialized functions that can regulate a wide spectrum of processes ranging from propagation of disease ...
Jenna L, Dziki +2 more
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Glucose Concentration in Subcutaneous Extracellular Space
Diabetes Care, 1993OBJECTIVE To compare the subcutaneous glucose sensor measurements with two reference methods. Previous studies provide conflicting findings about the real glucose concentrations in subcutaneous tissue. Some suggest substantially lower concentration, whereas others measure proportionally higher glucose concentrations
SCHMIDT, FJ, SLUITER, WJ, SCHOONEN, AJM
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Extracellular space determination in gallbladder mucosa
Biochimica et Biophysica Acta (BBA) - General Subjects, 1975Abstract Sucrose seems to be the best marker of the extracellular space in gallbladder mucosa. Inulin space is always smaller than sucrose space and the difference seems to be due to a sweeping-away effect in the intercellular channels as metabolic inhibitors and ouabain reduce it. Mannitol space continuously increases and this substance is likely to
D, Cremaschi, S, Hénin
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2001 interactions? An extracellular space odyssey
Current Opinion in Neurobiology, 1991Abstract Recent investigation has revealed an incredible degree of complexity in the types and functions of extracellular matrix molecules and their cellular receptors in the nervous system.
K J, Tomaselli, K M, Neugebauer
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The extracellular space of the lens
Experimental Eye Research, 1965The extracellular space of rat, rabbit and calf lenses has been estimated in vitro using radioactive non-metabolized carbohydrates and 24Na as test substances. The size of the extracellular space ranges from 4 to 13% of the lens water, depending on the test substance used.
R A, Thoft, J H, Kinoshita
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Tracking extracellular space in the brain
Science, 2016Neuroscience Extracellular space takes up a large percentage of the brain. Its size changes with the sleep-wake cycle but also during brain development and normal aging, as well as under pathological conditions such as neurodegeneration. Godin et al. injected near-infrared luminescent carbon nanotubes into rat brains and tracked their diffusion in the ...
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Extracellular space diffusion and pathological states
2000Publisher Summary There is increasing evidence that long-term changes in the physical and chemical parameters of the extracellular space (ECS) accompany many physiological and pathological states. The acute or relatively fast changes in the size of the intercellular channels are apparently a consequence of cellular (particularly glial) swelling ...
E, Syková +4 more
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