Determination of Extracellular Space in Amphibian Muscle [PDF]
The volumes of distribution of inulin and dextran in the sartorius, stomach, and cardiac muscle of the frog agree rather closely. That these spaces represent the volume of extracellular water is supported by the observation that efflux of sucrose can be divided into a fast and a slow phase and that the fast-moving fraction corresponds closely with ...
Emil Bozler
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Chronic alcohol consumption alters extracellular space geometry and transmitter diffusion in the brain. [PDF]
The alcohol-induced inflammatory response increases the diffusion range of small molecules in the extracellular brain parenchyma. Already moderate alcohol consumption has detrimental long-term effects on brain function.
De Santis S +14 more
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The Extracellular Space of Voluntary Muscle Tissues [PDF]
The volume occupied by the extracellular space has been investigated in six types of voluntary muscles: sartorius (frog), semitendinosus (frog), tibialis anticus longus (frog), iliofibularis (frog), rectus abdominis (frog), and diaphragm (rat). With the aid of four types of probe material, three of which are conventionally employed (inulin, sorbitol ...
Gilbert N. Ling, Marsha H. Kromash
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Extracellular space preservation aids the connectomic analysis of neural circuits
Dense connectomic mapping of neuronal circuits is limited by the time and effort required to analyze 3D electron microscopy (EM) datasets. Algorithms designed to automate image segmentation suffer from substantial error rates and require significant ...
Marta Pallotto +4 more
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Nanoscale and functional heterogeneity of the hippocampal extracellular space
Summary: The extracellular space (ECS) and its constituents play a crucial role in brain development, plasticity, circadian rhythm, and behavior, as well as brain diseases.
Diego Grassi +7 more
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Extracellular space in some isolated tissues [PDF]
1. The spaces occupied by isotopically labelled inulin, polyethylene glycol, mol. wt. 4000 (PEG 4000), polyethylene glycol, mol. wt. 1000 (PEG 1000) and sucrose in metabolizing mammalian kidney and liver slices and in toad bladder epithelial cell preparations incubated in vitro have been examined.2.
Donald J.L. McIver +1 more
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Imaging of the Entry Pathway of a Cell-Penetrating Peptide–DNA Complex From the Extracellular Space to Chloroplast Nucleoids Across Multiple Membranes in Arabidopsis Leaves [PDF]
Each plant cell has hundreds of copies of the chloroplast genome and chloroplast transgenes do not undergo silencing. Therefore, chloroplast transformation has many powerful potential agricultural and industrial applications.
Kazusato Oikawa +6 more
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Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space [PDF]
Neurons in developing sensory pathways exhibit spontaneous bursts of electrical activity that are critical for survival, maturation and circuit refinement.
Travis A Babola +3 more
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Demonstration of extracellular space by freeze-drying in the cerebellar molecular layer [PDF]
In electron micrographs of the molecular layer of the mouse cerebellum frozen within 30 sec of circulatory arrest and subsequently dried at -79 °C an appreciable extracellular space was found between the axons of the granular cells.
A. Van Harreveld, S. K. Malhotra
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Aquaporin-4–dependent K+ and water transport modeled in brain extracellular space following neuroexcitation [PDF]
Potassium (K+) ions released into brain extracellular space (ECS) during neuroexcitation are efficiently taken up by astrocytes. Deletion of astrocyte water channel aquaporin-4 (AQP4) in mice alters neuroexcitation by reducing ECS [K+] accumulation and ...
Byung‐Ju Jin +3 more
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