Results 271 to 280 of about 319,764 (352)

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

Calibration of Flow Cytometers Enables Reproducible Measurements of Extracellular Vesicle Concentrations and Reference Range Establishment. [PDF]

J Extracell Vesicles
Bettin BA, Li B, Falkena K, van Leeuwen TG, Gollwitzer C, Varga Z, Ajzenberg N, Antovic JP, Berckmans P, Buzas EI, Carney RP, Cook S, Dignat-George F, Faille D, Giebel B, Jones JC, Kim Y, Lacroix R, Lannigan J, Lucien F, Maaninka K, de Menezes EGM, Meyer A, Mizenko RR, Nelissen I, Nolan J, Norris PJ, Pink D, Poudel S, Robert S, Siljander PR, Tang VA, Tertel T, Broeck TVD, Wang L, Welsh JA, Nieuwland R, van der Pol E.   +37 more
europepmc   +1 more source

Hepatocyte‐Derived Extracellular Vesicles Deliver miR‐328‐3p to Trigger PP2A‐B56δ–Mediated p‐NLRP3S295‐Dependent Metaflammation in Macrophages upon Microcystin‐LR Exposure

Advanced Science, EarlyView.
Hepatocyte‐derived extracellular vesicles deliver miR‐328‐3p to trigger PP2A‐B56δ–mediated p‐NLRP3S295‐dependent metaflammation in macrophages upon microcystin‐LR exposure. 2‐DG, 2‐deoxy‐D‐glucose. B56δ, protein phosphatase 2A‐B56δ. ER, endoplasmic reticulum. iHD‐EV, inducible hepatocyte‐derived extracellular vesicles. IP3R, inositol 1,4,5‐triphosphate
Jia‐Shen Wu, Xin‐Yu Zhang, Xin‐Yu Ma, Yue‐Yue Wei, Lei‐Lei Wang, Ze‐Bang Du, Xiao‐Gang Xia, Lin Che, Dong‐Bei Guo, Han‐Ying Zheng, You‐Liang Yao, Wen‐Gang Li, Yu‐Chun Lin, Zhong‐Ning Lin   +13 more
wiley   +1 more source

Therapeutic extracellular vesicle preparation <i>via</i> sequential electrophoretic enrichment and counterflow microdialysis.

Lab Chip
Mehraji S, Pirolli NH, Nowak R, Jay SM, DeVoe DL.   +4 more
europepmc   +1 more source

Characteristics of extracellular vesicle-derived lncRNAs during the progression of HBV-related hepatocellular carcinoma. [PDF]

BMC Cancer
Ma Y, Lou C, Liang J, Guo C, Zhang J, Lu C, Zhang J, Gao Y.   +7 more
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Head-to-head comparison of extracellular vesicles from different cell sources for cardiac repair

Extracellular Vesicle
Kaiyue Zhang, Ke Cheng
doaj   +1 more source

Substrate Stiffness Modulates Fibroblast Extracellular Vesicle Secretion Via Mechanotransduction Pathways. [PDF]

Small
Yang J, Celebi LE, Hawthorne L, Ozcebe SG, Zorlutuna P.   +4 more
europepmc   +1 more source

Mechanical Environment Afforded by Engineered Hydrogel Critically Regulates Survival of Neural Stem Cells Transplanted in the Injured Spinal Cord via Piezo1‐Mediated Mechanotransduction

Advanced Science, EarlyView.
Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park, Yurim Kim, Byeong Seong Jang, Simay Genişcan, Dong Hoon Hwang, Yeojin Seo, Seung‐Ah Jee, Hyo Gyeong Seo, Hyung Soon Kim, Ariandokht Einisadr, Ho‐Jeong Kim, Seolhee Lee, Sangwoo Kwon, Kyung Sook Kim, Kang In Lee, Jae Young Lee, Joo Min Park, Young‐Min Kim, Soo‐Chang Song, Byung Gon Kim   +19 more
wiley   +1 more source

3D Nanofibrillar Matrix Stiffness Modulates Extracellular Vesicle Cargo and Pro-Tumour Functions. [PDF]

J Extracell Vesicles
Wang Z, Wang Z, Xie X, Zhou Y, He H, Guo Z, Zhou Z, Liu B, Sun J, Li W, Nie Q, Dai J, Yi W, Zhou X, Yan J, Yang M.   +15 more
europepmc   +1 more source