Results 11 to 20 of about 1,172,315 (295)

Biological properties of extracellular vesicles and their physiological functions

open access: yesJournal of Extracellular Vesicles, 2015
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity to transfer proteins, lipids and nucleic acids, thereby influencing
M. Yáñez-Mó   +66 more
semanticscholar   +1 more source

The roles of extracellular vesicles in the immune system

open access: yesNature reviews. Immunology, 2022
Extracellular vesicles (EVs) are increasingly recognized as having ubiquitous roles in the immune system. This Review focuses on the progress made in the field in the past 5 years, including the roles of EVs in innate and adaptive immunity and their ...
E. Buzás
semanticscholar   +1 more source

Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment [PDF]

open access: yes, 2019
The glioblastoma is the most malignant form of brain cancer. Glioblastoma cells use multiple ways of communication with the tumor microenvironment in order to tune it for their own benefit.
Pastor Loro, Ángel Manuel   +1 more
core   +1 more source

Clinical Translation of Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, 2023
Extracellular vesicles (EVs) occur in a variety of bodily fluids and have gained recent attraction as natural materials due to their bioactive surfaces, internal cargo, and role in intercellular communication.
Aayushi Ghodasara   +4 more
semanticscholar   +1 more source

RNA delivery by extracellular vesicles in mammalian cells and its applications

open access: yesNature reviews. Molecular cell biology, 2020
The term ‘extracellular vesicles’ refers to a heterogeneous population of vesicular bodies of cellular origin that derive either from the endosomal compartment (exosomes) or as a result of shedding from the plasma membrane (microvesicles, oncosomes and ...
Killian O’Brien   +4 more
semanticscholar   +1 more source

Porous microneedle patch with sustained delivery of extracellular vesicles mitigates severe spinal cord injury

open access: yesNature Communications, 2023
The transplantation of mesenchymal stem cells-derived secretome, particularly extracellular vesicles is a promising therapy to suppress spinal cord injury-triggered neuroinflammation.
Ao Fang   +21 more
semanticscholar   +1 more source

Extracellular vesicles: Exosomes, microvesicles, and friends

open access: yesJournal of Cell Biology, 2013
Cells release into the extracellular environment diverse types of membrane vesicles of endosomal and plasma membrane origin called exosomes and microvesicles, respectively.
G. Raposo, W. Stoorvogel
semanticscholar   +1 more source

Extracellular vesicles: New players in cardiovascular diseases [PDF]

open access: yes, 2014
Extracellular vesicles, particles released by all cell types, represent a new way to convey information between cells such as proteins, second messengers, and genetic information to modify the phenotype and function of the target cells.
A. Gaceb   +2 more
core   +3 more sources

Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis

open access: yesCells, 2019
The use of extracellular vesicles, specifically exosomes, as carriers of biomarkers in extracellular spaces has been well demonstrated. Despite their promising potential, the use of exosomes in the clinical setting is restricted due to the lack of ...
Laura M Doyle, Michael Zhuo Wang
semanticscholar   +1 more source

Extracellular vesicles engineering by silicates-activated endothelial progenitor cells for myocardial infarction treatment in male mice

open access: yesNature Communications, 2023
Extracellular vesicles have shown good potential in disease treatments including ischemic injury such as myocardial infarction. However, the efficient production of highly active extracellular vesicles is one of the critical limitations for their ...
Bin Yu   +11 more
semanticscholar   +1 more source

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