Results 11 to 20 of about 244,743 (291)

Understanding extracellular vesicles [PDF]

PROTEOMICS, 2021
No description ...
David W. Greening, Richard J. Simpson
openaire   +2 more sources

Extracellular Vesicles in Neuroinflammation [PDF]

Frontiers in Cell and Developmental Biology, 2021
Extracellular vesicles (EVs) are a heterogenous group of membrane-bound particles that play a pivotal role in cell–cell communication, not only participating in many physiological processes, but also contributing to the pathogenesis of several diseases.
Marostica G., Gelibter S., Gironi M., Nigro A., Furlan R.   +4 more
openaire   +3 more sources

Ciliary extracellular vesicles are distinct from the cytosolic extracellular vesicles [PDF]

Journal of Extracellular Vesicles, 2021
AbstractExtracellular vesicles (EVs) are cell‐derived membrane vesicles that are released into the extracellular space. EVs encapsulate key proteins and mediate intercellular signalling pathways. Recently, primary cilia have been shown to release EVs under fluid‐shear flow, but many proteins encapsulated in these vesicles have never been identified ...
Mohieldin, Ashraf M., Pala, Rajasekharreddy, Beuttler, Richard, Moresco, James J., Yates, John R., III, Nauli, Surya M.   +5 more
openaire   +7 more sources

Extracellular Vesicles in Transplantation [PDF]

Frontiers in Immunology, 2022
Extracellular vesicles (EVs) have been extensively studied in the last two decades. It is now well documented that they can actively participate in the activation or regulation of immune system functions through different mechanisms, the most studied of which include protein–protein interactions and miRNA transfers.
Nicolas Sailliet, Matti Ullah, Amandine Dupuy, Amanda K. A. Silva, Florence Gazeau, Hoa Le Mai, Sophie Brouard, Sophie Brouard   +7 more
openaire   +5 more sources

Preeclampsia and Extracellular Vesicles [PDF]

Current Hypertension Reports, 2016
Preeclampsia is a hypertensive pregnancy disorder characterized by development of hypertension and proteinuria after 20 weeks of gestation that remains a leading cause of maternal and neonatal morbidity and mortality. While preeclampsia is believed to result from complex interactions between maternal and placental factors, the proximate pathophysiology
Gilani, Sarwat I., Weissgerber, Tracey L., Garovic, Vesna D., Jayachandran, Muthuvel   +3 more
openaire   +2 more sources

Extracellular vesicles

GENETICS
Abstract Extracellular vesicles (EVs) encompass a diverse array of membrane-bound organelles released outside cells in response to developmental and physiological cell needs. EVs play important roles in remodeling the shape and content of differentiating cells and can rescue damaged cells from toxic or dysfunctional content. EVs can send
Juan Wang, Maureen M Barr, Ann M Wehman
  +8 more sources

SnapShot: Extracellular Vesicles

Cell, 2020
Cells release a variety of extracellular vesicles (EVs; including exosomes, microvesicles, and many others) into their environment. EVs can bud in endosomes or directly at the plasma membrane, carrying a selection of components from the cell and displaying various functional properties.
Cocozza, Federico, Grisard, Eleonora, Martin-Jaular, Lorena, Mathieu, Mathilde, Théry, Clotilde   +4 more
openaire   +2 more sources

Dosing extracellular vesicles

Advanced Drug Delivery Reviews, 2021
Extracellular vesicles (EVs) are natural nanoparticles containing biologically active molecules. They are important mediators of intercellular communication and can be exploited therapeutically by various bioengineering approaches. To accurately determine the therapeutic potential of EVs in pre-clinical and clinical settings, dependable dosing ...
Gupta, Dhanu, Zickler, Antje Maria, El Andaloussi, Samir   +2 more
openaire   +2 more sources

Extracellular Vesicles in Phylogeny

International Journal of Molecular Sciences, 2023
Extracellular vesicles (EVs) are cell-derived lipid vesicles in a size range of 20–1000 nm; often, these are classified as smaller and larger EVs in the literature or also commonly called small EVs (“exosomes”) and medium/large EVs (“microvesicles”) [...]
openaire   +2 more sources

Metalloproteinases in extracellular vesicles

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2017
Extracellular vesicles (EVs) have emerged as pivotal mediators of intercellular communications in local and distant microenvironments under patho/physiological conditions. EVs contain bioactive materials such as proteins, RNA transcripts, microRNAs and even DNAs, and recent work on their protein profiles has revealed the existence of metalloproteinases
Masayuki, Shimoda, Rama, Khokha
openaire   +2 more sources