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Understanding extracellular vesicles [PDF]
PROTEOMICS, 2021 No description ...
David W. Greening, Richard J. Simpson
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Advanced Drug Delivery Reviews, 2021 Extracellular vesicles (EVs) are natural nanoparticles containing biologically active molecules. They are important mediators of intercellular communication and can be exploited therapeutically by various bioengineering approaches. To accurately determine the therapeutic potential of EVs in pre-clinical and clinical settings, dependable dosing ...
Gupta, Dhanu +2 more
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GENETICSAbstract Extracellular vesicles (EVs) encompass a diverse array of membrane-bound organelles released outside cells in response to developmental and physiological cell needs. EVs play important roles in remodeling the shape and content of differentiating cells and can rescue damaged cells from toxic or dysfunctional content. EVs can send
Juan Wang, Maureen M Barr, Ann M Wehman
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SnapShot: Extracellular Vesicles
Cell, 2020 Cells release a variety of extracellular vesicles (EVs; including exosomes, microvesicles, and many others) into their environment. EVs can bud in endosomes or directly at the plasma membrane, carrying a selection of components from the cell and displaying various functional properties.
Cocozza, Federico +4 more
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Extracellular Vesicles—Connecting Kingdoms [PDF]
International Journal of Molecular Sciences, 2019 It is known that extracellular vesicles (EVs) are shed from cells of almost every type of cell or organism, showing their ubiquity in all empires of life. EVs are defined as naturally released particles from cells, delimited by a lipid bilayer, and cannot replicate. These nano- to micrometer scaled spheres shuttle a set of bioactive molecules.
Eric Woith +2 more
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Extracellular Vesicles in Neuroinflammation [PDF]
Frontiers in Cell and Developmental Biology, 2021 Extracellular vesicles (EVs) are a heterogenous group of membrane-bound particles that play a pivotal role in cell–cell communication, not only participating in many physiological processes, but also contributing to the pathogenesis of several diseases.
Marostica G. +4 more
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Preeclampsia and Extracellular Vesicles [PDF]
Current Hypertension Reports, 2016 Preeclampsia is a hypertensive pregnancy disorder characterized by development of hypertension and proteinuria after 20 weeks of gestation that remains a leading cause of maternal and neonatal morbidity and mortality. While preeclampsia is believed to result from complex interactions between maternal and placental factors, the proximate pathophysiology
Gilani, Sarwat I. +3 more
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Scientific Reports, 2021 HIV and type 2 diabetes (T2D) are both associated with gut microbiota alterations, low-grade endotoxemia and increased cardiovascular risk. We investigated the potential role of plasma extracellular vesicles (EVs) in relation to these processes.
Beate Vestad +12 more
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Single Extracellular VEsicle Nanoscopy
Journal of Extracellular Vesicles, 2023 AbstractExtracellular vesicles (EVs) and their cargo constitute novel biomarkers. EV subpopulations have been defined not only by abundant tetraspanins (e.g., CD9, CD63 and CD81) but also by specific markers derived from their source cells. However, it remains a challenge to robustly isolate and characterize EV subpopulations.
Andras Saftics +10 more
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Exploring differential gene expression and biomarker potential in systemic lupus erythematosus: a retrospective study [PDF]
PeerJBackground Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by inflammation and immune-mediated multi-organ system damage, accompanied by clinical manifestations such as fever, hair loss, skin rash, oral ulcers, and joint ...
Jie Xiao +9 more
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