Results 31 to 40 of about 759,843 (300)

Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy

Journal of Extracellular Vesicles, 2021
Gram‐positive bacteria ubiquitously produce membrane vesicles (MVs), and although they contribute to biological functions, our knowledge regarding their composition and immunogenicity remains limited.
Natalie J. Bitto, Lesley Cheng, Ella L. Johnston, Rishi Pathirana, Thanh Kha Phan, Ivan K. H. Poon, Neil M. O'Brien‐Simpson, Andrew F. Hill, Timothy P. Stinear, Maria Kaparakis‐Liaskos   +9 more
doaj   +1 more source

Brain endothelium-derived extracellular vesicles containing amyloid-beta induce mitochondrial alterations in neural progenitor cells

, 2022
Aim: Elevated brain deposits of amyloid beta (Aβ40) contribute to neuropathology and cognitive dysfunction in Alzheimer’s disease (AD). However, the role of the blood-brain barrier (BBB) as an interface for the transfer of Aβ40 from the periphery into ...
Kowalczyk, Jennifer M, Louis, Kelssey D Pierre, Daftari, Manav T, Dykxhoorn, Derek M, Daftari, Manav T., Colbert, Brett M., Toborek, Michal, Kowalczyk, Jennifer M., András, Ibolya E., Dykxhoorn, Derek M., Colbert, Brett M, Torices, Silvia, Pierre Louis, Kelssey D., Osborne, Olivia M, András, Ibolya E, Naranjo, Oandy, Osborne, Olivia M.   +16 more
core   +1 more source

Protein Biocargo and Anti-Inflammatory Effect of Tomato Fruit-Derived Nanovesicles Separated by Density Gradient Ultracentrifugation and Loaded with Curcumin

Pharmaceutics, 2023
Plant-derived nanovesicles (PDNVs) have become attractive alternatives to mammalian cell-derived extracellular vesicles (EVs) both as therapeutic approaches and drug-delivery vehicles.
Ramila Mammadova, Serena Maggio, Immacolata Fiume, Ramesh Bokka, Maneea Moubarak, Gabriella Gellén, Gitta Schlosser, Giorgia Adamo, Antonella Bongiovanni, Francesco Trepiccione, Michele Guescini, Gabriella Pocsfalvi   +11 more
doaj   +1 more source

Metalloproteinases in extracellular vesicles

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2017
Extracellular vesicles (EVs) have emerged as pivotal mediators of intercellular communications in local and distant microenvironments under patho/physiological conditions. EVs contain bioactive materials such as proteins, RNA transcripts, microRNAs and even DNAs, and recent work on their protein profiles has revealed the existence of metalloproteinases
Masayuki, Shimoda, Rama, Khokha
openaire   +2 more sources

Highlights of the São Paulo ISEV workshop on extracellular vesicles in cross-kingdom communication [PDF]

, 2017
In the past years, extracellular vesicles (EVs) have become an important field of research since EVs have been found to play a central role in biological processes.
Puccia, R., Hansen, E.P., Bergese, P., Marcilla, A., Pereira-Chioccola, V., Nejsum, P., Øvstebø, R., Witwer, K., de la Canal, L., Soares, R.P., Schenkman, S., Colli, W., da Silva, L.L.P., Pfaffl, M.W., Criado, M.F., Del Portillo, H., Stensballe, A., Menezes-Neto, A., Olivier, M., Torrecilhas, A.C., Xander, P., Alves, M.J.M., Jaular, L.M., Nolte-T Hoen, E., Fritz, J., Ferreira, K.S., Gho, Y.S., Abdel Baqui, M.M., Riesbeck, K., Wauben, M., Costa, A.O.   +30 more
core   +2 more sources

Biomanufacturing of Tomato-Derived Nanovesicles

Foods, 2020
Micro- and nano-sized vesicles (MVs and NVs, respectively) from edible plant resources are gaining increasing interest as green, sustainable, and biocompatible materials for the development of next-generation delivery vectors.
Ramesh Bokka, Anna Paulina Ramos, Immacolata Fiume, Mauro Manno, Samuele Raccosta, Lilla Turiák, Simon Sugár, Giorgia Adamo, Tamás Csizmadia, Gabriella Pocsfalvi   +9 more
doaj   +1 more source

The relationship between chronic immune response and neurodegenerative damage in long COVID-19

Frontiers in Immunology, 2022
In the past two years, the world has faced the pandemic caused by the severe acute respiratory syndrome 2 coronavirus (SARS-CoV-2), which by August of 2022 has infected around 619 million people and caused the death of 6.55 million individuals globally ...
José Pedro Elizalde-Díaz, Clara Leticia Miranda-Narváez, Juan Carlos Martínez-Lazcano, Eduardo Martínez-Martínez   +3 more
doaj   +1 more source

Extracellular Vesicles as Regulators of the Extracellular Matrix

Bioengineering, 2023
Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids, proteins, and lipids to facilitate cell-to-cell communication. As EVs are released and move from parent to recipient cell, EVs interact with the extracellular matrix (ECM) which ...
Neil J. Patel, Anisa Ashraf, Eun Ji Chung   +2 more
openaire   +3 more sources

Extracellular Vesicles Mediate Epimastigogenesis in Trypanosoma cruzi: Strain-Specific Dynamics and Temperature-Dependent Differentiation

Life
Trypanosoma cruzi, the causative agent of Chagas disease, undergoes epimastigogenesis—a critical differentiation step in which trypomastigotes transform into epimastigotes. While this process is essential for the parasite’s survival in its insect vector,
Abel Sana, Izadora Volpato Rossi, Bruna Sabatke, Marcel Ivan Ramirez   +3 more
doaj   +1 more source

Exploring differential gene expression and biomarker potential in systemic lupus erythematosus: a retrospective study [PDF]

PeerJ
Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by inflammation and immune-mediated multi-organ system damage, accompanied by clinical manifestations such as fever, hair loss, skin rash, oral ulcers, and joint ...
Jie Xiao, Yuhong Luo, Lina Duan, Xinru Mao, Lingyue Jin, Haifang Wang, Hongxia Wang, Jie Pan, Ying Gong, Haixia Li   +9 more
doaj   +2 more sources