Results 11 to 20 of about 1,190,807 (310)

Immunogenicity of Extracellular Vesicles

Advanced Materials
Extracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery systems due to demonstrated safety and efficacy in preclinical models and early‐stage clinical trials. There is an urgent need to address the immunogenicity of EVs (
Yutian Xia, Jianzhong Zhang, Gang Liu, Joy Wolfram   +3 more
semanticscholar   +5 more sources

Dosing Extracellular Vesicles.

Advanced Drug Delivery Reviews, 2021
Extracellular vesicles (EVs) are natural nanoparticles containing biologically active molecules. They are important mediators of intercellular communication and can be exploited therapeutically by various bioengineering approaches.
Dhanu Gupta, Antje Maria Zickler, S. El Andaloussi   +2 more
semanticscholar   +3 more sources

Extracellular Vesicles in Neuroinflammation [PDF]

Frontiers in Cell and Developmental Biology, 2021
Extracellular vesicles (EVs) are a heterogenous group of membrane-bound particles that play a pivotal role in cell–cell communication, not only participating in many physiological processes, but also contributing to the pathogenesis of several diseases.
Marostica G., Gelibter S., Gironi M., Nigro A., Furlan R.   +4 more
openaire   +3 more sources

Ciliary extracellular vesicles are distinct from the cytosolic extracellular vesicles [PDF]

Journal of Extracellular Vesicles, 2021
AbstractExtracellular vesicles (EVs) are cell‐derived membrane vesicles that are released into the extracellular space. EVs encapsulate key proteins and mediate intercellular signalling pathways. Recently, primary cilia have been shown to release EVs under fluid‐shear flow, but many proteins encapsulated in these vesicles have never been identified ...
Mohieldin, Ashraf M., Pala, Rajasekharreddy, Beuttler, Richard, Moresco, James J., Yates, John R., III, Nauli, Surya M.   +5 more
openaire   +7 more sources

Preeclampsia and Extracellular Vesicles [PDF]

Current Hypertension Reports, 2016
Preeclampsia is a hypertensive pregnancy disorder characterized by development of hypertension and proteinuria after 20 weeks of gestation that remains a leading cause of maternal and neonatal morbidity and mortality. While preeclampsia is believed to result from complex interactions between maternal and placental factors, the proximate pathophysiology
Gilani, Sarwat I., Weissgerber, Tracey L., Garovic, Vesna D., Jayachandran, Muthuvel   +3 more
openaire   +2 more sources

SnapShot: Extracellular Vesicles

Cell, 2020
Cells release a variety of extracellular vesicles (EVs; including exosomes, microvesicles, and many others) into their environment. EVs can bud in endosomes or directly at the plasma membrane, carrying a selection of components from the cell and displaying various functional properties.
Cocozza, Federico, Grisard, Eleonora, Martin-Jaular, Lorena, Mathieu, Mathilde, Théry, Clotilde   +4 more
openaire   +2 more sources

Extracellular Vesicles in Transplantation [PDF]

Frontiers in Immunology, 2022
Extracellular vesicles (EVs) have been extensively studied in the last two decades. It is now well documented that they can actively participate in the activation or regulation of immune system functions through different mechanisms, the most studied of which include protein–protein interactions and miRNA transfers.
Nicolas Sailliet, Matti Ullah, Amandine Dupuy, Amanda K. A. Silva, Florence Gazeau, Hoa Le Mai, Sophie Brouard, Sophie Brouard   +7 more
openaire   +5 more sources

Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy

Journal of Extracellular Vesicles, 2021
Gram‐positive bacteria ubiquitously produce membrane vesicles (MVs), and although they contribute to biological functions, our knowledge regarding their composition and immunogenicity remains limited.
Natalie J. Bitto, Lesley Cheng, Ella L. Johnston, Rishi Pathirana, Thanh Kha Phan, Ivan K. H. Poon, Neil M. O'Brien‐Simpson, Andrew F. Hill, Timothy P. Stinear, Maria Kaparakis‐Liaskos   +9 more
doaj   +1 more source

Protein Biocargo and Anti-Inflammatory Effect of Tomato Fruit-Derived Nanovesicles Separated by Density Gradient Ultracentrifugation and Loaded with Curcumin

Pharmaceutics, 2023
Plant-derived nanovesicles (PDNVs) have become attractive alternatives to mammalian cell-derived extracellular vesicles (EVs) both as therapeutic approaches and drug-delivery vehicles.
Ramila Mammadova, Serena Maggio, Immacolata Fiume, Ramesh Bokka, Maneea Moubarak, Gabriella Gellén, Gitta Schlosser, Giorgia Adamo, Antonella Bongiovanni, Francesco Trepiccione, Michele Guescini, Gabriella Pocsfalvi   +11 more
doaj   +1 more source

Biological properties of extracellular vesicles and their physiological functions

Journal of Extracellular Vesicles, 2015
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity to transfer proteins, lipids and nucleic acids, thereby influencing
M. Yáñez-Mó, P. Siljander, Zoraida Andreu, A. B. Zavec, F. Borràs, E. Buzás, K. Buzas, K. Buzas, Enriqueta Casal, F. Cappello, J. Carvalho, J. Carvalho, E. Colás, Anabela Cordeiro da Silva, Anabela Cordeiro da Silva, S. Fais, J. Falcón-Pérez, I. Ghobrial, B. Giebel, M. Gimona, M. Graner, I. Gursel, M. Gursel, N. Heegaard, N. Heegaard, A. Hendrix, P. Kierulf, K. Kokubun, Maja Kosanović, V. Kralj-Iglič, Eva-Maria Krämer-Albers, S. Laitinen, Cecilia Lässer, T. Lener, E. Ligeti, A. Linē, G. Lipps, A. Llorente, J. Lötvall, Mateja Manček-Keber, A. Marcilla, M. Mittelbrunn, I. Nazarenko, E. N. Hoen, T. Nyman, L. O’Driscoll, M. Oliván, Carla Oliveira, Carla Oliveira, É. Pállinger, H. A. Portillo, J. Reventós, M. Rigau, E. Rohde, M. Sammar, F. Sánchez‐Madrid, N. Santarém, N. Santarém, K. Schallmoser, M. S. Ostenfeld, W. Stoorvogel, Roman Štukelj, S. Grein, M. Vasconcelos, M. Vasconcelos, M. Wauben, O. Wever   +66 more
semanticscholar   +1 more source