Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity
Summary: Cancer extracellular vesicles (EVs) are highly heterogeneous, which impedes our understanding of their function as intercellular communication agents and biomarkers.
Aron Gyuris +11 more
doaj +1 more source
Impact of Chemotherapy on Extracellular Vesicles: Understanding the Chemo-EVs [PDF]
Chemotherapy is the standard go-to treatment for cancer besides surgery and radiation. It has recently come to light that the interaction between chemotherapy and the immune system is important in maintaining tumor immunity as well as influencing the efficacy of the therapy.
Nur' Syahada Ab Razak +3 more
openaire +3 more sources
The role of Notch pathway in the pro-tumorigenic activity of extracellular vesicles in multiple myeloma [PDF]
Introduction: Multiple myeloma (MM) is characterized by the tight interaction between MM cells and bone barrow (BM) niche, resulting in tumor progression.
Domenica Giannandrea +12 more
core +1 more source
IFNT-independent effects of intrauterine extracellular vesicles (EVs) in cattle [PDF]
Abstract Extracellular vesicles (EVs) present in uterine lumen are involved in conceptus-endometrial interactions during the pre-implantation period. Despite numerous studies conducted on interferon tau (IFNT), a major protein of maternal recognition of pregnancy, the effect of intrauterine EVs on the endometrium during pre ...
Keigo, Nakamura +4 more
openaire +2 more sources
Cryo-electron microscopy of extracellular vesicles from cerebrospinal fluid.
Extracellular vesicles (EVs) are membrane-enclosed vesicles which play important role for cell communication and physiology. EVs are found in many human biological fluids, including blood, breast milk, urine, cerebrospinal fluid (CSF), ejaculate, saliva ...
Anton Emelyanov +10 more
doaj +1 more source
EVs-miRNA: The New Molecular Markers for Chronic Respiratory Diseases
Idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), asthma and sleep disorders are chronic respiratory diseases that affect the airways, compromising lung function over time.
Piera Soccio +6 more
doaj +1 more source
Potentials and capabilities of the Extracellular Vesicle (EV) Array
Extracellular vesicles (EVs) and exosomes are difficult to enrich or purify from biofluids, hence quantification and phenotyping of these are tedious and inaccurate. The multiplexed, highly sensitive and high‐throughput platform of the EV Array presented by Jørgensen et al., (J Extracell Vesicles, 2013; 2: 10) has been refined regarding the ...
Jørgensen, Malene Møller; id_orcid 0000-0003-1381-3863 +2 more
openaire +4 more sources
An ex vivo model of interactions between extracellular vesicles and peripheral mononuclear blood cells in whole blood [PDF]
Extracellular vesicles (EVs) can be loaded with therapeutic cargo and engineered for retention by specific body sites; therefore, they have great potential for targeted delivery of biomolecules to treat diseases.
Carlson, Bess +12 more
core
Summary: Subventricular zone (SVZ) neural stem cells (NSCs) are the cornerstone of the perinatal neurogenic niche. Microglia are immune cells of the nervous system that are enriched in the neonatal SVZ.
Mary C. Morton +4 more
doaj +1 more source
Extracellular signals regulate the biogenesis of extracellular vesicles
Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of proteins and RNAs for intercellular communication. With various biomolecules and specific ligands, EV has represented a novel form of information transfer ...
Yong Jin +5 more
doaj +1 more source

