Results 41 to 50 of about 859,861 (224)

Potentials and capabilities of the Extracellular Vesicle (EV) Array

Journal of Extracellular Vesicles, 2015
Extracellular vesicles (EVs) and exosomes are difficult to enrich or purify from biofluids, hence quantification and phenotyping of these are tedious and inaccurate. The multiplexed, highly sensitive and high‐throughput platform of the EV Array presented by Jørgensen et al., (J Extracell Vesicles, 2013; 2: 10) has been refined regarding the ...
Jørgensen, Malene Møller; id_orcid 0000-0003-1381-3863, Bæk, Rikke, Varming, Kim   +2 more
openaire   +4 more sources

Neonatal Subventricular Zone Neural Stem Cells Release Extracellular Vesicles that Act as a Microglial Morphogen

Cell Reports, 2018
Summary: Subventricular zone (SVZ) neural stem cells (NSCs) are the cornerstone of the perinatal neurogenic niche. Microglia are immune cells of the nervous system that are enriched in the neonatal SVZ.
Mary C. Morton, Victoria N. Neckles, Caitlin M. Seluzicki, Jennie C. Holmberg, David M. Feliciano   +4 more
doaj   +1 more source

EVs-miRNA: The New Molecular Markers for Chronic Respiratory Diseases

Life, 2022
Idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), asthma and sleep disorders are chronic respiratory diseases that affect the airways, compromising lung function over time.
Piera Soccio, Giorgia Moriondo, Donato Lacedonia, Pasquale Tondo, Carla Maria Irene Quarato, Maria Pia Foschino Barbaro, Giulia Scioscia   +6 more
doaj   +1 more source

Quantitative proteomic analysis of small and large extracellular vesicles (EVs) reveals enrichment of adhesion proteins in small EVs.

Journal of Proteome Research, 2019
Extracellular vesicles (EVs) are important mediators of cell-cell communication due to their cargo content of proteins, lipids and RNAs. We previously reported that small EVs (SEVs) called exosomes promote directed and random cell motility, invasion, and
Lizandra Jimenez, Hui-Feng Yu, A. McKenzie, J. Franklin, J. G. Patton, Qi Liu, Alissa M. Weaver   +6 more
semanticscholar   +1 more source

Brain endothelium-derived extracellular vesicles containing amyloid-beta induce mitochondrial alterations in neural progenitor cells

, 2022
Aim: Elevated brain deposits of amyloid beta (Aβ40) contribute to neuropathology and cognitive dysfunction in Alzheimer’s disease (AD). However, the role of the blood-brain barrier (BBB) as an interface for the transfer of Aβ40 from the periphery into ...
Kowalczyk, Jennifer M, Louis, Kelssey D Pierre, Daftari, Manav T, Dykxhoorn, Derek M, Daftari, Manav T., Colbert, Brett M., Toborek, Michal, Kowalczyk, Jennifer M., András, Ibolya E., Dykxhoorn, Derek M., Colbert, Brett M, Torices, Silvia, Pierre Louis, Kelssey D., Osborne, Olivia M, András, Ibolya E, Naranjo, Oandy, Osborne, Olivia M.   +16 more
core   +1 more source

IFNT-independent effects of intrauterine extracellular vesicles (EVs) in cattle [PDF]

Reproduction, 2020
Abstract Extracellular vesicles (EVs) present in uterine lumen are involved in conceptus-endometrial interactions during the pre-implantation period. Despite numerous studies conducted on interferon tau (IFNT), a major protein of maternal recognition of pregnancy, the effect of intrauterine EVs on the endometrium during pre ...
Keigo, Nakamura, Kazuya, Kusama, Atsushi, Ideta, Kazuhiko, Imakawa, Masatoshi, Hori   +4 more
openaire   +2 more sources

Role of Extracellular Vesicles (EVs) in Cell Stress Response and Resistance to Cancer Therapy

Cancers, 2019
Extracellular vesicles (EVs) are nanosized particles released by all cells that have been heralded as novel regulators of cell-to-cell communication. It is becoming increasingly clear that in response to a variety of stress conditions, cells employ EV ...
Clodagh P. O’Neill, K. Gilligan, R. Dwyer   +2 more
semanticscholar   +1 more source

Extracellular Vesicles

, 2022
Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling.
İşlek, Zeynep, Bozkurt, Batuhan Turhan, Üçışık, Mehmet Hikmet, Şahin, Fikrettin   +3 more
core   +1 more source

A Single Extracellular Vesicle (EV) Flow Cytometry Approach to Reveal EV Heterogeneity [PDF]

Angewandte Chemie International Edition, 2018
AbstractExtracellular vesicles (EVs) actively participate in intercellular communication and pathological processes. Studying the molecular signatures of EVs is key to reveal their biological functions and clinical values, which, however, is greatly hindered by their sub‐100 nm dimensions, the low quantities of biomolecules each EV carries, and the ...
Wen Shen, Kaizhu Guo, Gary Brent Adkins, Qiaoshi Jiang, Yang Liu, Sabrina Sedano, Yaokai Duan, Wei Yan, Shizhen Emily Wang, Kristina Bergersen, Danielle Worth, Emma H. Wilson, Wenwan Zhong   +12 more
openaire   +5 more sources

Engineered EVs for Oxidative Stress Protection

Pharmaceuticals, 2021
Extracellular vesicles (EVs) are increasingly studied as vectors for drug delivery because they can transfer a variety of molecules across biological barriers. SerpinB3 is a serine protease inhibitor that has shown a protective anti-apoptotic function in
Anna Maria Tolomeo, Santina Quarta, Alessandra Biasiolo, Mariagrazia Ruvoletto, Michela Pozzobon, Giada De Lazzari, Ricardo Malvicini, Cristian Turato, Giorgio Arrigoni, Patrizia Pontisso, Maurizio Muraca   +10 more
doaj   +1 more source