Distinct non‐coding RNA cargo of extracellular vesicles from M1 and M2 human primary macrophages [PDF]
Macrophages are important antigen presenting cells which can release extracellular vesicles (EVs) carrying functional cargo including non‐coding RNAs. Macrophages can be broadly classified into M1 ‘classical’ and M2 ‘alternatively‐activated’ macrophages.
Clements, Toby +11 more
core +1 more source
The Role of Extracellular Vesicles in Cancer
Intercellular communication is a key feature of cancer progression and metastasis. Extracellular vesicles (EVs) are generated by all cells, including cancer cells and recent studies have identified EVs as key mediators of cell-cell communication via ...
R. Kalluri, K. McAndrews
semanticscholar +1 more source
Reproducibility of extracellular vesicle research [PDF]
Cells release membrane-delimited particles into the environment. These particles are called “extracellular vesicles” (EVs), and EVs are present in fluids contacting cells, including body fluids and conditioned culture media.
Witwer, Kenneth W. +7 more
core +1 more source
Extracellular vesicles: a rising star for therapeutics and drug delivery
Various current techniques for isolating extracellular vesicles are reviewed, and their advantages and disadvantages are compared. An overview of the strategies used for the modification of extracellular vesicles and their application as delivery systems
S. Du +8 more
semanticscholar +1 more source
Extracellular vesicles: Exosomes, microvesicles, and friends
Cells release into the extracellular environment diverse types of membrane vesicles of endosomal and plasma membrane origin called exosomes and microvesicles, respectively.
G. Raposo, W. Stoorvogel
semanticscholar +1 more source
Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies [PDF]
Recent studies suggest both normal and cancerous cells secrete vesicles into the extracellular space. These extracellular vesicles (EVs) contain materials that mirror the genetic and proteomic content of the secreting cell. The identification of cancer-specific material in EVs isolated from the biofluids (e.g., serum, cerebrospinal fluid, urine) of ...
Johnny C, Akers +4 more
openaire +2 more sources
Supplementation with small-extracellular vesicles from ovarian follicular fluid during in vitro production modulates bovine embryo development. [PDF]
Pregnancy success results from the interaction of multiple factors, among them are folliculogenesis and early embryonic development. Failure during these different processes can lead to difficulties in conception.
Juliano C da Silveira +14 more
doaj +1 more source
The Ambiguous Roles of Extracellular Vesicles in HIV Replication and Pathogenesis
Cells from all kingdoms of life can release membrane-enclosed vesicles to the extracellular milieu. These extracellular vesicles (EVs) may function as mediators of intercellular communication, allowing the transfer of biologically active molecules ...
Marcos V. S. Dias +5 more
doaj +1 more source
EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research
We argue that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate interpretation and replication of experiments. To achieve this, we describe EV-TRACK, a crowdsourcing knowledgebase (http://evtrack.org) that centralizes EV biology and methodology with the goal of stimulating authors, reviewers, editors and ...
Consortium, EV-TRACK +95 more
openaire +8 more sources
Tumour-Derived Extracellular Vesicles (EVs): A Dangerous “Message in A Bottle” for Bone [PDF]
Several studies have shown the importance of Extracellular Vesicles (EVs) in the intercellular communication between tumour and resident cells. Through EVs, tumour cells can trigger cell-signalling molecules and shuttle exogenous information to target cells, thus promoting spread of the disease.
Cappariello A., Rucci N.
openaire +2 more sources

