Results 91 to 100 of about 140,375 (300)
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Research Progress on the Functions and Applications of Prunus domestica L. Processing Wastes and Their Active Components [PDF]
Prunus domestica L., a member of the genus Prunus of the family Rosaceae, is known as a “third-generation functional fruit” due to its high nutritional value.
HE Pan, LU Min, YAN Jie, WEI Die, XI Meng, GU Xin
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Innovative methods of extracting the loose gold from technogenic deposits in the Irkutsk region
In Russia and abroad, the scope of the use of gold has significantly expanded, which undoubtedly affected the level of production. However, despite the fairly high rates of gold mining, the economic situation that has developed in recent years makes the ...
Golovina Elena +2 more
doaj +1 more source
Citrus processing industry generates the large amount of byproducts, which are rich in polyphenols that have high antioxidant properties. These polyphenols can be extracted and utilized in different applications.
Anuradha Saini, P. Panesar, M. B. Bera
semanticscholar +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Leveraging LLMs for legal terms extraction with limited annotated data
The legal industry is characterized by the presence of dense and complex documents, which necessitate automatic processing methods to manage and analyse large volumes of data.
Julien Breton +6 more
semanticscholar +1 more source
Chamomile, a well-known medicinal plant, is a rich source of bioactive compounds, among which two coumarin derivatives, umbelliferone and herniarin, are often found in its extracts.
M. Molnar +4 more
semanticscholar +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Zanthoxylum bungeanum is native to China and is a traditional food seasoning and traditional Chinese medicine. It plays an important role in food processing and disease prevention. In this article, the research progress of Z.
QU Yanfeng +4 more
doaj +1 more source

