Results 101 to 110 of about 11,735,145 (343)

On the fidelity of the core mass functions derived from dust column density data [PDF]

, 2009
Aims: We examine the recoverability and completeness limits of the dense core mass functions (CMFs) derived for a molecular cloud using extinction data and a core identification scheme based on two-dimensional thresholding.
Alves, Bohlin, C. J. Lada, Evans, J. F. Alves, J. Kainulainen, J. M. Rathborne, Johnstone, Johnstone, Johnstone, Johnstone, Kroupa, Lada, Lombardi, Lombardi, Lombardi, Lombardi, Mathis, Motte, Motte, Nutter, Reid, Reid, Rosolowsky, Salpeter, Simpson, Stanke, Testi, Wilking, Williams   +29 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Statistical Tools to Optimize the Recovery of Bioactive Compounds from Marine Byproducts

Marine Drugs
Techniques for extracting important bioactive molecules from seafood byproducts, viz., bones, heads, skin, frames, fins, shells, guts, and viscera, are receiving emphasis due to the need for better valorization.
Zenebe Tadesse Tsegay, Sofia Agriopoulou, Moufida Chaari, Slim Smaoui, Theodoros Varzakas   +4 more
doaj   +1 more source

Statistical Analysis to Extract Effective Parameters on Overall Energy Consumption of Wireless Sensor Network (WSN)

, 2012
In this paper, we use statistical tools to analysis dependency between Wireless Sensor Network (WSN) parameters and overall Energy Consumption (EC). Our approach has two main phases: profiling, and effective parameter extraction.
Hoang, Doan B., Kamyabpour, Najmeh
core   +1 more source

Development of response surface methodology for optimization of extraction parameters and quantitative estimation of embelin from Embelia ribes Burm by high performance liquid chromatography

Pharmacognosy Magazine, 2015
Background: Embelia ribes Burm is widely used medicinal plant for the treatment of different types of disorders in the Indian traditional systems of medicine.
Md. Shamsir Alam, Z. Damanhouri, Aftab Ahmad, L. Abidin, M. Amir, M. Aqil, Shahalam Khan, M. Mujeeb   +7 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The Effect of Extraction Solvents, Temperature and Time on the Composition and Mass Fraction of Polyphenols in Dalmatian Wild Sage (Salvia officinalis L.) Extracts

Food Technology and Biotechnology, 2013
The effect of extraction solvents (30, 50 and 70 % aqueous solutions of ethanol and acetone, and 100 % distilled water), extraction temperature (60 and 90 °C) and extraction time (30, 60 and 90 min) on the composition and mass fraction of polyphenolic ...
Maja Dent, Marija Penić, Tomislav Bosiljkov, Branka Levaj, Verica Dragović-Uzelac   +4 more
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

CMB Polarization Data and Galactic Foregrounds: Estimation of Cosmological Parameters [PDF]

, 1999
We estimate the accuracy with which various cosmological parameters can be determined from the CMB temperature and polarization data when various galactic unpolarized and polarized foregrounds are included and marginalized using the multi-frequency ...
Bond J. R., Borrill J., Bouchet F. R., Efstathiou G., F. R. Bouchet, Knox L., Lesgourgues J., Lineweaver C. H., Muciaccia P. F., Prunet S., S. K. Sethi, S. Prunet, Starobinsky A. A., Tegmark M., Tegmark M., Tegmark M., Toffolatti L., Zaldarriaga M.   +17 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source