dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Optimization of Extraction Parameters for Enhanced Recovery of Bioactive Compounds from Quince Peels Using Response Surface Methodology. [PDF]
Athanasiadis V +5 more
europepmc +1 more source
Automated extraction of oscillation parameters for Kepler observations of solar-type stars
The recent launch of the Kepler space telescope brings the opportunity to study oscillations systematically in large numbers of solar-like stars. In the framework of the asteroFLAG project, we have developed an automated pipeline to estimate global ...
Arentoft, Torben +6 more
core
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Optimization of Extraction Parameters and Characterization of Tunisian Date Extract: A Scientific Approach Toward Their Utilization. [PDF]
Messadi N +5 more
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Systematic evaluation and optimization of protein extraction parameters in diagnostic FFPE specimens. [PDF]
Dressler FF +7 more
europepmc +1 more source
Road Extraction by Deep Residual U-Net
Road extraction from aerial images has been a hot research topic in the field of remote sensing image analysis. In this letter, a semantic segmentation neural network which combines the strengths of residual learning and U-Net is proposed for road area ...
Liu, Qingjie +2 more
core +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Optimization of Conventional Extraction Parameters for Recovering Phenolic Compounds from Potato (Solanum tuberosum L.) Peels and Their Application as an Antioxidant in Yogurt Formulation. [PDF]
Brahmi F +8 more
europepmc +1 more source

