Results 121 to 130 of about 34,294 (314)

Limits of Ordered Graphs and their Applications

open access: yes, 2019
The emerging theory of graph limits exhibits an analytic perspective on graphs, showing that many important concepts and tools in graph theory and its applications can be described more naturally (and sometimes proved more easily) in analytic language ...
Ben-Eliezer, Omri   +3 more
core  

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

open access: yesAdvanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang   +15 more
wiley   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

Global Evidence of the Unimodal Response of Ecosystem Respiration to Soil Moisture

open access: yesAdvanced Science, EarlyView.
Using global eddy covariance observations and a field experiment, this paper provides compelling evidence for the widespread unimodal relationship between soil moisture and ecosystem respiration and its water adaptation. Such knowledge facilitates understanding of soil moisture in affecting respiratory carbon emissions and has the potential to improve ...
Jinlong Peng   +9 more
wiley   +1 more source

Undecidability of polynomial inequalities in weighted graph homomorphism densities

open access: yesForum of Mathematics, Sigma
Many problems and conjectures in extremal combinatorics concern polynomial inequalities between homomorphism densities of graphs where we allow edges to have real weights.
Grigoriy Blekherman   +2 more
doaj   +1 more source

Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection

open access: yesAdvanced Science, EarlyView.
Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Hye‐Won Shim   +10 more
wiley   +1 more source

On $ \mathsf{{H}} $-intersecting graph families and counting of homomorphisms

open access: yesAIMS Mathematics
This work derives an upper bound on the maximum cardinality of a family of graphs on a fixed number of vertices, in which the intersection of every two graphs in that family contains a subgraph that is isomorphic to a specified graph $ \mathsf{{H ...
Igal Sason
doaj   +1 more source

Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm

open access: yesAdvanced Science, EarlyView.
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang   +22 more
wiley   +1 more source

A Mars Local Terrain Matching Method Based on 3D Point Clouds

open access: yesRemote Sensing
To address the matching challenge between the High Resolution Imaging Science Experiment (HiRISE) Digital Elevation Model (DEM) and the Mars Orbiter Laser Altimeter (MOLA) DEM, we propose a terrain matching framework based on the combination of point ...
Binliang Wang   +3 more
doaj   +1 more source

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