Results 31 to 40 of about 146,732 (216)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

NILAI EKONOMI ANAK, MOTIVASI, DAN SELF-ESTEEM PEKERJA ANAK

open access: yesJurnal Ilmu Keluarga dan Konsumen, 2013
Analysis of influence of the child’s economic value and motivation on self-esteem of child labor in one of the business center in Bogor District was the goal of this research.
Robi Rizkianto   +2 more
doaj   +1 more source

Extrinsic stressors modulate resource evaluations: insights from territoriality under artificial noise

open access: yesFrontiers in Zoology, 2021
Background Competition is considered to rely on the value attributed to resources by animals, but the influence of extrinsic stressors on this value remains unexplored.
Kyriacos Kareklas   +2 more
doaj   +1 more source

Correlation of teacher extrinsic factors on teacher performance during online learning in Aceh Besar

open access: yesAl-Ishlah: Jurnal Pendidikan, 2022
Online learning that is carried out simultaneously affects the world of education. The extrinsic and intrinsic factors of the teacher's personality become one of the problem factors in the learning process.
Maulida Maulida, Hasanuddin Hasanuddin
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

The Role of Self-Efficacy, Task Value, and Intrinsic and Extrinsic Motivations in Students’ Feedback Engagement in English Learning

open access: yesBehavioral Sciences, 2023
Drawing on Wigfield and Eccles’s motivational theory, which is acclaimed for explaining individual behavioral intentions, this study investigated the extent to which different forms of motivation (i.e., self-efficacy, task value, and intrinsic and ...
Zhengdong Gan, Fulan Liu, Honghan Nang
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Consumers’ Perceived Value of Pork Meat: A Segmentation on Intrinsic and Extrinsic Cues

open access: yesFoods
This study aimed to determine the intrinsic and extrinsic product cues affecting consumers’ perceived value of pork meat. A segmentation study of seventeen intrinsic (n = 103) and twenty-six extrinsic cues (n = 114) on a South African sample was ...
Diewald Jordaan   +2 more
doaj   +1 more source

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