Results 31 to 40 of about 146,732 (216)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
NILAI EKONOMI ANAK, MOTIVASI, DAN SELF-ESTEEM PEKERJA ANAK
Analysis of influence of the child’s economic value and motivation on self-esteem of child labor in one of the business center in Bogor District was the goal of this research.
Robi Rizkianto +2 more
doaj +1 more source
Background Competition is considered to rely on the value attributed to resources by animals, but the influence of extrinsic stressors on this value remains unexplored.
Kyriacos Kareklas +2 more
doaj +1 more source
Correlation of teacher extrinsic factors on teacher performance during online learning in Aceh Besar
Online learning that is carried out simultaneously affects the world of education. The extrinsic and intrinsic factors of the teacher's personality become one of the problem factors in the learning process.
Maulida Maulida, Hasanuddin Hasanuddin
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Drawing on Wigfield and Eccles’s motivational theory, which is acclaimed for explaining individual behavioral intentions, this study investigated the extent to which different forms of motivation (i.e., self-efficacy, task value, and intrinsic and ...
Zhengdong Gan, Fulan Liu, Honghan Nang
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Consumers’ Perceived Value of Pork Meat: A Segmentation on Intrinsic and Extrinsic Cues
This study aimed to determine the intrinsic and extrinsic product cues affecting consumers’ perceived value of pork meat. A segmentation study of seventeen intrinsic (n = 103) and twenty-six extrinsic cues (n = 114) on a South African sample was ...
Diewald Jordaan +2 more
doaj +1 more source

