Results 61 to 70 of about 401,468 (341)

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Possibility of Isolated Mung Bean Protein as a Main Raw Material in the Production of an Extruded High-Moisture Meat Analog

Foods
As consumer demand for meat analogs continues to grow, various plant proteins are being explored for their production. This study uses isolated mung bean protein (IMBP) to replace isolated soy protein (ISP), investigating the effects of IMBP content (0%,
Nam-Ki Hwang, Bon-Jae Gu, Yu Zhang, Gi-Hyung Ryu   +3 more
doaj   +1 more source

Quality prediction of internal thread cold extrusion based on genetic algorithm optimized BP neural network

Advances in Mechanical Engineering, 2022
The extrusion process parameters have a great impact on the quality of the extrusion thread. In order to ensure the extrusion quality and the smooth progress of the extrusion process, a prediction model based on BP-GA neural network is established.
Hong-Ling Hou, Guang-Peng Zhang, Xin Chen, Yong-Qiang Zhao   +3 more
doaj   +1 more source

A new engineering method for understanding extrusion cooking process [PDF]

, 2009
A new engineering method is proposed to understand extrudate expansion and extrusion operation parameters for starch based food extrusion cooking process through dimensional analysis principle, i.e. Buckingham pi theorem. Three dimensionless groups, i.e.
Cheng, Hongyuan, Friis, Alan
core  

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Effect of W Contents and Annealing Temperatures on the Microstructure and Mechanical Properties of CoFeNi Medium Entropy Alloys

Metals
In this work, the W element, with a larger atomic radius compared to Co, Fe, and Ni, was added to modify the microstructure and enhance the yield strength of CoFeNi medium entropy alloy (MEA).
Yaqi Cui, Huan Ma, Li Yang, Yang Shao, Renguo Guan   +4 more
doaj   +1 more source

Simulation of gelled propellant doughs isothermal flow through extrusion dies using finite difference method [PDF]

, 2017
During the ram extrusion of gelled propellants, the possible flow instabilities can affect the extruded propellant quality. The numerical modelling helps to enhance the geometry of extrusion die, by minimizing the product distortion caused by material ...
Faura Mateu, Félix, Franco Chumillas, Patricio, López García, Pedro José, Martínez Pastor, Juan, Moratilla Fernández, Domingo   +4 more
core   +2 more sources

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

Optimization of High-Moisture Meat Analog Production with the Addition of Isolated Mung Bean Protein Using Response Surface Methodology

Foods
Meat analogs focus on sustainable development, mimicking the physical properties and nutritional components of meat. The main objective of this study was to determine the optimal extrusion process parameters for producing high-moisture meat analogs ...
Yu Zhang, Bon-Jae Gu, Nam-ki Hwang, Gi-Hyung Ryu   +3 more
doaj   +1 more source