Results 51 to 60 of about 369,995 (299)

Dislocation behavior and strengthening mechanisms of Cu–Te alloy drawn at room and cryogenic temperatures

Journal of Materials Research and Technology, 2023
In the work, the cryogenic and room temperature drawing behaviors of Cu–Te alloy with a wide range of accumulative drawing true strain up to 1.1 are systematically investigated. For the first time, the storage of geometrically necessary dislocations (GND)
Qianqian Fu, Bing Li, Hongwang Fu, Minqiang Gao, Changfeng Wang, Ying Fu, Renguo Guan   +6 more
doaj   +1 more source

A general extrudate bulk density model for both twin-screw and single-screw extruder extrusion cooking processes [PDF]

, 2010
Effects of extrusion parameters and raw materials on extrudate expansion are respectively investigated in a twin-screw extruder and a single-screw extruder extrusion cooking experiments for fish feed, wheat, and oat & wheat mixture processing.
Cheng, Hongyuan, Friis, Alan, Høeg Hansen, Jonas, Tolderlund Rasmussen, Hanne   +3 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Energetics and Mechanism of Drug Transport Mediated by the Lactococcal Multidrug Transporter LmrP [PDF]

, 1996
The gene encoding the secondary multidrug transporter LmrP of Lactococcus lactis was heterologously expressed in Escherichia coli. The energetics and mechanism of drug extrusion mediated by LmrP were studied in membrane vesicles of E. coli. LmrP-mediated
Bolhuis, Henk,, Brands, Jan Roel,, Driessen, Arnold J.M.,, Konings, Wil N.,, Poolman, Bert,, Putman, Monique,, Veen, Hendrik W. van,   +6 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Simulation of gelled propellant doughs isothermal flow through extrusion dies using finite difference method [PDF]

, 2017
During the ram extrusion of gelled propellants, the possible flow instabilities can affect the extruded propellant quality. The numerical modelling helps to enhance the geometry of extrusion die, by minimizing the product distortion caused by material ...
Faura Mateu, Félix, Franco Chumillas, Patricio, López García, Pedro José, Martínez Pastor, Juan, Moratilla Fernández, Domingo   +4 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Microstructure Evolution and Solidification Behavior of a Novel Semi-Solid Alloy Slurry Prepared by Vibrating Contraction Inclined Plate

Metals, 2021
In this work, based on the A356 alloy, a novel Al–Si–Mg–Cu–Fe–Sr alloy with good mechanical property and high thermal conductivity was developed. The semi-solid slurry of the alloy was prepared via the vibrating contraction inclined plate.
Yan Liu, Minqiang Gao, Ying Fu, Weirong Li, Pan Yang, Renguo Guan   +5 more
doaj   +1 more source

Effect of frictional boundary conditions and percentage area reduction on the extrusion pressure of Aluminum AA6063 alloy using FE analysis modelling [PDF]

, 2020
© 2020 by the authors; licensee Growing Science, Canada. This is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).Finite Element Analysis ...
Ismail, Sikiru O., Jen, T. C., Oyinbo, S. T.   +2 more
core   +2 more sources