Results 61 to 70 of about 369,995 (299)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Enhanced comprehensive performance via alloying and rheo-diecasting in a semi-solid Al–Si–Fe–Mg–Cu–Sr alloy

open access: yesJournal of Materials Research and Technology, 2023
A semi-solid Al alloy with superior comprehensive performance was obtained via alloying design concept and rheo-diecasting (RDC). The semi-solid alloy slurry was obtained via the vibrating contraction sloping plate.
Yan Liu   +5 more
doaj   +1 more source

Influence of choked angle of bearing channel on profile grain structure during multi-hole extrusion of aluminum alloy [PDF]

open access: yes, 2018
Direct extrusion of aluminum alloy EN AW-6060 was carried out applying a four-hole die with pair-wise parallel and choked long channels. Due to the dissimilar friction inside parallel and choked channels profiles with different length were extruded ...
Müller, Sören, Sanabria, Vidal
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Role of Starch Type in Gel-like Network Formation of Extruded Meat Analogs

open access: yesGels
Starches play a crucial role in determining the expansion, texture, and structural development of extruded meat analogs through their gelatinization behavior and interactions with proteins.
Chaeyeon Kang, Ayeon Han, Bon-Jae Gu
doaj   +1 more source

Rapid billet loader aids extrusion of refractory metals [PDF]

open access: yes, 1964
A combination gravity and manually powered rapid billet loader reduces the time required for transferring hot metal billets from a heating furnace to an extrusion press.
Dolinshek, A. F., Herman, L. E.
core   +1 more source

Evaluation of magnetic resonance imaging guidelines for differentiation between thoracolumbar intervertebral disk extrusions and intervertebral disk protrusions in dogs [PDF]

open access: yes, 2016
Four MRI variables have recently been suggested to be independently associated with a diagnosis of thoracolumbar intervertebral disk extrusion or protrusion.
Aikawa   +48 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Thermoreflectance Detection of Point Defects Resulting from Focused Ion Beam Milling

open access: yesAdvanced Engineering Materials, EarlyView.
Focused ion beam (FIB) milling is a common tool for nanoscale material processing, however irradiation damage, redeposition, and contamination can occur. We use several characterization tools to show FIB‐induced effects beyond 1 mm from the milled area.
Thomas W. Pfeifer   +3 more
wiley   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

open access: yesAdvanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai   +2 more
wiley   +1 more source

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