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Software eyes for protein post‐translational modifications

Mass Spectrometry Reviews, 2014
Post‐translational modifications (PTMs) are critical to almost all aspects of complex processes of the cell. Identification of PTMs is one of the biggest challenges for proteomics, and there have been many computational studies for the analysis of PTMs from tandem mass spectrometry (MS/MS).
Seungjin, Na, Eunok, Paek
openaire   +2 more sources

Keeping an Eye on Bardet-Biedl Syndrome: A Comprehensive Review of the Role of Bardet-Biedl Syndrome Genes in the Eye

Medical Research Archives, 2017
Upwards of 90% of individuals with Bardet-Biedl syndrome (BBS) display rod-cone dystrophy with early macular involvement. BBS is an autosomal recessive, genetically heterogeneous, pleiotropic ciliopathy for which 21 causative genes have been discovered ...
Katie Weihbrecht   +7 more
semanticscholar   +1 more source

Proteins in tears from healthy and diseased eyes

Documenta Ophthalmologica, 1980
The levels of total protein in tears from healthy donors, conjunctivitis vernalis patients, and conjunctivitis follicularis patients, were 625, 1370 and 1160 mg% respectively. Serum albumin accounted for 3.3%, 43% and 67% of the total protein of tears from these groups, and the level of proteins probably synthesized by the lacrimal gland, was in tears ...
A, Zavaro   +3 more
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Serotonin induced protein phosphorylation in the aplysia eye

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1987
Serotonin (5-HT) increases the phosphorylation of two low molecular weight phosphoproteins of 23,000 and 15,000 daltons molecular weight and decreases the phosphorylation of a 20,000 dalton phosphoprotein in the isolated Aplysia eye. The cAMP analog 8-benzylthio cAMP increases and decreases the phosphorylation of the 23,000 and 20,000 dalton 5-HT ...
D P, Lotshaw, J W, Jacklet
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Permeability of the eye lens capsule of the bigeye tuna to nuclear eye lens proteins

Comparative Biochemistry and Physiology, 1970
Abstract 1. 1. Protein was extracted from lens nuclei of bigeye and skipjack tunas, dolphin fish and one species of squid. 2. 2. Total concentration and electrophoretic characteristics of the protein were determined in extracts which were not enclosed or were partially enclosed in bigeye lens capsule for 24 hr. 3. 3. High molecular weight
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Aqueous Humor Protein and Complement in Pseudophakic Eyes

Cornea, 1990
Intraocular lens (IOL) insertion is now the standard method of aphakic correction in this country. Previous studies have shown that an IOL can activate the alternative complement system of normal human serum in vitro, thereby generating peptides capable of stimulating inflammation that can result in visual morbidity in pseudophakic eyes.
A W, Tuberville, T O, Wood
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Catecholamine and protein synthesis in the eyes of Aplysia californica

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1977
Abstract 1. 1. The eyes of Aplysia californica were studied for their ability to synthesize proteins and catecholamines. 2. 2. Using high voltage electrophoresis two peaks which co-migrate with dopa and dopamine incorporated 14C tyrosine, suggesting dopamine as a putative neurotransmitter in the eye. 3. 3.
Y P, Loh, J W, Jacklet
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The soluble proteins of the prenatal bovine eye lens

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1974
Abstract 1. 1. Lenses of bovine embryos and fetuses, ranging in age from 6 weeks to 9 months, were investigated. 2. 2. Weight, shape, protein content and protein composition as well as leucine aminopeptidase activity were determined as a function of age. 3. 3. Alpha-crystallin turned out to be the most prominent embryonic crystallin. 4.
G J, Van Kamp   +2 more
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Membrane Protein Expression in the Eyes of Transgenic Flies

2009
Eukaryotic membrane proteins are often difficult to obtain in sufficient amounts for structural studies using classical cell culture overexpression systems. This could be due to incomplete protein maturation and insufficient trafficking to the plasma membrane or to a cytotoxic effect of the recombinant membrane protein changing the overall metabolism ...
Valérie, Panneels, Irmgard, Sinning
openaire   +2 more sources

ANALYSIS OF TEAR PROTEIN PATTERNS FOR THE DIAGNOSIS OF "DRY EYE"

Cornea, 2000
Dry eye syndrome occurs very frequently in the industrial world. In the United States, one of five people, 59 millions patients, suffer from symptoms of this disease (Eagle Vision, Yankelovich and Partners, 1997), and the number of patients has doubled in the last 10 years. 1-4 Diagnosis and treatment of dry eye syndrome are challenging.
Franz H, Grus   +3 more
openaire   +2 more sources

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