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ANALYSIS OF TEAR PROTEIN PATTERNS FOR THE DIAGNOSIS OF "DRY EYE"

Cornea, 2000
Dry eye syndrome occurs very frequently in the industrial world. In the United States, one of five people, 59 millions patients, suffer from symptoms of this disease (Eagle Vision, Yankelovich and Partners, 1997), and the number of patients has doubled in the last 10 years. 1-4 Diagnosis and treatment of dry eye syndrome are challenging.
Franz H, Grus   +3 more
openaire   +2 more sources

Fusion Proteins: Aflibercept (VEGF Trap-Eye)

2015
Vascular endothelial growth factor (VEGF) inhibitors currently used to treat eye diseases have included monoclonal antibodies, antibody fragments, and an aptamer. A different method of achieving VEGF blockade in retinal diseases includes the concept of a cytokine trap.
Salman, Sarwar   +7 more
openaire   +2 more sources

Eye Lens Proteins and Cataracts

2007
At first sight, the lens of the eye would appear to be an ideal environment for amyloid fibril formation. The protein concentration is the highest of any tissue in the body, the proteins are very long-lived, present in slightly acidic conditions and subjected over time to extensive truncation and post-translational modification.
openaire   +1 more source

Eye diseases and proteins controlling visual transduction

Biochimie, 1987
Retinal S antigen is a soluble protein found in abundance in photoreceptor cells. Immunization of laboratory animals with this antigen in adjuvant induces experimental autoimmune uveoretinitis. Cellular immunity plays a major role in this condition. Autoimmune responses toward retinal S antigen are often observed in patients with retinal inflammatory ...
openaire   +2 more sources

Eye-Lens proteins structure, superstructure, stability, genetics

Naturwissenschaften, 1994
The eye lens in vertebrates and invertebrates is an avascular tissue which allows one to focus objects on the retina. The lens grows throughout life, maintaining transparency without significant turnover of its densely packed proteins. Apart from cytoskeletal and taxon-specific components, these proteins belong mainly to the alpha- and beta gamma ...
openaire   +2 more sources

Inflammatory proteins associated with contact lens-related dry eye

Contact Lens and Anterior Eye, 2022
Safal Khanal, Jason J Nichols
exaly  

Proteins through the eyes of an organic chemist

Tetrahedron, 2022
Shaswati Mandal, Ashraf Brik
openaire   +1 more source

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