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Eye Lens Proteins and Cataracts
2007At first sight, the lens of the eye would appear to be an ideal environment for amyloid fibril formation. The protein concentration is the highest of any tissue in the body, the proteins are very long-lived, present in slightly acidic conditions and subjected over time to extensive truncation and post-translational modification.
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Fusion Proteins: Aflibercept (VEGF Trap-Eye)
2015Vascular endothelial growth factor (VEGF) inhibitors currently used to treat eye diseases have included monoclonal antibodies, antibody fragments, and an aptamer. A different method of achieving VEGF blockade in retinal diseases includes the concept of a cytokine trap.
Salman, Sarwar +7 more
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Eye diseases and proteins controlling visual transduction
Biochimie, 1987Retinal S antigen is a soluble protein found in abundance in photoreceptor cells. Immunization of laboratory animals with this antigen in adjuvant induces experimental autoimmune uveoretinitis. Cellular immunity plays a major role in this condition. Autoimmune responses toward retinal S antigen are often observed in patients with retinal inflammatory ...
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Protein delivery to the back of the eye: barriers, carriers and stability of anti-VEGF proteins.
Drug Discovery Today, 2017K. Radhakrishnan +6 more
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Eye-Lens proteins structure, superstructure, stability, genetics
Naturwissenschaften, 1994The eye lens in vertebrates and invertebrates is an avascular tissue which allows one to focus objects on the retina. The lens grows throughout life, maintaining transparency without significant turnover of its densely packed proteins. Apart from cytoskeletal and taxon-specific components, these proteins belong mainly to the alpha- and beta gamma ...
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Inflammatory proteins associated with contact lens-related dry eye
Contact Lens and Anterior Eye, 2022Safal Khanal, Jason Nichols
exaly
Protein Dynamics in the Eye Studied with Labelled Proteins
American Journal of Ophthalmology, 1959openaire +2 more sources
Aptamer-based plasmonic sensor array for discrimination of proteins and cells with the naked eye.
Analytical Chemistry, 2013Yuexiang Lu +5 more
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THE HOMOGENEITY OF THE LENS OF THE EYE WITH REGARD TO PROTEIN
Acta Ophthalmologica, 1951openaire +2 more sources
Autophagy in the eye: Development, degeneration, and aging.
Progress in retinal and eye research, 2016P. Boya +4 more
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