Results 61 to 70 of about 19,637 (185)

The pivotal role of cholesterol absorption inhibitors in the management of dyslipidemia

Lipids in Health and Disease, 2004
Elevated low-density lipoprotein (LDL)-cholesterol is associated with a significantly increased risk of coronary heart disease. Ezetimibe is the first member of a new class of selective cholesterol absorption inhibitors.
Suleiman Ehab S, Choueiri Nabil E, Al-Shaer Moutasim H   +2 more
doaj   +1 more source

Mechanical Thrombus Aspiration for a Young STEMI Patient With Plaque Erosion: Time for a Stent‐Free Approach?

Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 833-839, September 1, 2026.
ABSTRACT A 34‐year‐old man with no cardiovascular history presented with anterior ST‐elevation myocardial infarction and a large thrombotic occlusion of the mid left anterior descending artery. Following potent antithrombotic therapy and mechanical thrombus aspiration, angiography revealed vessel patency without residual significant stenosis, allowing ...
Domenico Simone Castiello, Francesco Greco, Antonio Curcio, Alberto Polimeni   +3 more
wiley   +1 more source

Ezetimibe: New perspectives in lipid lowering treatment [PDF]

, 2007
Therapeutic goals for lipid lowering treatment in the prevention of ischemic heart disease are often not reached in clinical practice. Even the highest doses of statins do not guarantee good control of hypercholesterolemia in all patients. Therefore, new
Jankowski, Piotr; 1^st Clinic of Cardiology University Hospital, Cracow, Poland, Kawecka-Jaszcz, Kalina, Loster, Magdalena   +2 more
core  

Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia [PDF]

, 2002
ObjectivesThe purpose of this study was to assess the efficacy and safety of ezetimibe administered with simvastatin in patients with primary hypercholesterolemia.BackgroundDespite the availability of statins, many patients do not achieve lipid targets ...
Suresh, Ramachandran, Davidson, Michael H, Sun, Steven, Lipka, Leslie J, LeBeaut, Alexandre P, Veltri, Enrico P, Bettis, Robert, Melani, Lorenzo, McGarry, Thomas   +8 more
core   +1 more source

PMcardio‐Assisted ECG Interpretation in Non‐ST‐Elevation Acute Coronary Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT A 53‐year‐old man presented with exertional chest pain. The electrocardiogram and PMcardio smartphone application flagged ischemic changes. Urgent coronary angiography revealed a thrombotic occlusion of the proximal right coronary artery, treated by percutaneous coronary intervention with two drug‐eluting stents and restoration of coronary ...
Kim Wouters, Atif Qureshi, Muhammad Sharjeel Abbas, Ramzi Zeidan, Priyavardhan Mishra, Murtaja Satea, Rinaldo Lauwers, Bipin Chaurasia   +7 more
wiley   +1 more source

Clinical efficacy and safety of Ezetimibe on major cardiovascular endpoints: systematic review and meta-analysis of randomized controlled trials.

PLoS ONE, 2015
BackgroundRandomized clinical trials (RCTs) about Ezetimibe's efficacy on patient-oriented outcomes have given discordant results. The aim of this study was to determine the net effect of Ezetimibe and of the widely marketed combination, Ezetimibe ...
Alessandro Battaggia, Alberto Donzelli, Maria Font, Davide Molteni, Antonio Galvano   +4 more
doaj   +1 more source

Ezetimibe prescriptions in older Canadian adults after an acute myocardial infarction: a population-based cohort study

Lipids in Health and Disease, 2018
Background The utility of ezetimibe in preventing cardiovascular outcomes remains controversial. To guide future assessments of the effectiveness of ezetimibe in routine care, we evaluated how this medication has been prescribed to high-risk older adults
Kristin K. Clemens, Salimah Z. Shariff, Eric McArthur, Robert A. Hegele   +3 more
doaj   +1 more source

Mechanistic Insights Into the Association Between Gut Microbiota Diversity and Atherosclerosis, Acute Coronary Syndrome, and Peripheral Arterial Disease Progression

Clinical Cardiology, Volume 49, Issue 9, September 2026.
Proposed gut‐vascular framework linking microbial ecology to atherosclerotic disease. Diet and related exposures shape dysbiosis or microbial resilience; resulting changes in SCFAs, TMAO, bile acids, and LPS may modulate endothelial function, immune activation, and platelet activity, contributing to atherosclerosis, ACS, and PAD.
Amr Ali Mohamed Abdelgawwad El‐Sehrawy, Usamah Sayed, Zarina Nasirova, Quvonch Tursunov, Omer Qutaiba B. Allela, Lara Asim Kzar, Rajashree Panigrahi, Neeraj Bainsal   +7 more
wiley   +1 more source

Ezetimibe inhibits expression of acid sphingomyelinase in liver and intestine

, 2009
Ezetimibe inhibits cholesterol absorption in the intestine. Sphingomyelin has strong interactions with cholesterol. We investigated the effects of ezetimibe on Sphingomyelinase (SMase) expression in intestine and liver. After feeding rats with ezetimibe (
Wu, Jun, Jun Wu, Duan, Rui-Dong, Yao Zhang, Rui‐Dong Duan, Liu, Fuli, Zhang, Yao, Yajun Cheng, Fuli Liu, Cheng, Yajun, Nilsson, Åke, Åke Nilsson   +11 more
core   +1 more source

Ezetimibe inhibits the migration and invasion of triple‐negative breast cancer cells by targeting TGFβ2 and EMT

FEBS Open Bio
The important role of cholesterol in tumor metastasis has been widely studied in recent years. Ezetimibe is currently the only selective cholesterol uptake inhibitor on the market.
Lingkai Kong, Qinyu He, Ding Ma, Weiwei Shi, Qilei Xin, Chunping Jiang, Junhua Wu   +6 more
doaj   +1 more source