Results 1 to 10 of about 248,012 (169)
BMC Infectious Diseases, 2022 Background Despite the development and application of vaccines against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) around the world, the scientific community is still trying to find some therapies to avoid or ameliorate the fatal ...
Carmen de la Rocha +20 more
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Revista de Ciências Agroveterinárias, 2023 As doenças parasitárias causadas por piolhos resistentes aos fármacos são causadoras de declínio na produtividade dos rebanhos ovinos no Nordeste do Brasil. Objetivou-se avaliar a eficácia “in vitro” de Amitraz 12,5%, Cipermetrina 15% e Ivermectina 0,5 %
Vanessa Maria de Sales Duarte +12 more
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Symposium 9: Beyond lifestyle changes. Pharmacological approach
Revista de la Sociedad Argentina de Diabetes, 2022 The prevalence of overweight and obesity in pediatrics has increased drastically in recent decades. This leads to a greater cardiometabolic, oncological, psychiatric burden and in the quality of life in adulthood.
Lidia Caracotche
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Revista de la Sociedad Argentina de Diabetes, 2022 Diabetes is one of the fastest growing diseases all over the world. However, the current therapeutic strategies have not been able to stop neither its progressive course nor its complications. One possible explanation might be that the diabetes diagnosis
Matías Re
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Assessment of mutations on RBD in the Spike protein of SARS-CoV-2 Alpha, Delta and Omicron variants
Scientific Reports, 2022 The severe acute respiratory syndrome (SARS) coronavirus 2 (CoV-2) variant Omicron spread more rapid than the other variants of SARS-CoV-2 virus. Mutations on the Spike (S) protein receptor-binding domain (RBD) are critical for the antibody resistance ...
Clauber Henrique Souza da Costa +3 more
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BMC Complementary Medicine and Therapies, 2020 Background Currently there is a high prevalence of humor disorders such as anxiety and depression throughout the world, especially concerning advanced age patients. Aniba riparia (Nees) Mez.
Sócrates Golzio dos Santos +9 more
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Synthesis and antimycobacterial evaluation of new gem- difluorohydrazides
Orbital: The Electronic Journal of Chemistry, 2012 Several gem-difluorohydrazides were prepared by the addition of nitrogen nucleophiles to N-acetyl-2,2-gem-difluoroxindoles substituted in position 5. Initially, commercial isatin was N-acetylated using acetic anhydride.
Frederico S. C. Branco +4 more
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A brief overview of current drug repurposing approaches for COVID-19 management [PDF]
, 2020 This brief overview is intended to shed light on the current drug repositioning (also called drug repurposing) in the therapeutics of the novel coronavirus disease which emerged in 2019 (COVID-19).
Rodrigues, Pedro da Fonseca Soares +1 more
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Spectroscopic and Theoretical Study of CuI Binding to His111 in the Human Prion Protein Fragment 106-115 [PDF]
, 2016 The ability of the cellular prion protein (PrPC) to bind copper in vivo points to a physiological role for PrPC in copper transport. Six copper binding sites have been identified in the nonstructured N-terminal region of human PrPC.
Alberto Vela +12 more
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Frontiers in Chemistry, 2019 Twenty new 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole analogs were synthetized to develop P2X7 receptor (P2X7R) inhibitors. P2X7R inhibition in vitro was evaluated in mouse peritoneal macrophages, HEK-293 cells transfected with hP2X7R (dye uptake assay), and ...
Daniel T. G. Gonzaga +16 more
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