Results 1 to 10 of about 258,478 (215)
Uso de fármacos psicoestimulantes en drogodependencias [PDF]
, 2006 El uso de medicamentos estimulantes es una cuestión de plena actualidad en psiquiatría, aunque su utilización y prescripción es controvertida . Fármacos como el metilfenidato, las anfetaminas, o el modafinilo están siendo utilizados y estudiados en ...
Casas, Miquel, Roncero, Carlos
core +7 more sources
Discovery of [1,2,4]triazolo[1,5-a]pyrimidine-Imatinib Hybrids With Selective Cytotoxic Activity: A Mechanistically Divergent Series From Direct BCR-ABL1 Inhibition. [PDF]
ChemMedChemDiscovery of imatinib–triazolopyrimidine hybrids with selective cytotoxicity and a mechanism distinct from classical BCR‐ABL1 inhibition. This bioisosteric strategy introduces a novel compounds, paving the way for innovative antileukemic therapies with differentiated profiles.
Moura SCB +10 more
europepmc +2 more sources
BMC Infectious Diseases, 2022 Background Despite the development and application of vaccines against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) around the world, the scientific community is still trying to find some therapies to avoid or ameliorate the fatal ...
Carmen de la Rocha +20 more
doaj +1 more source
The Oncologist, EarlyView., 2021 Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi +21 more
wiley +1 more source
Revista de Ciências Agroveterinárias, 2023 As doenças parasitárias causadas por piolhos resistentes aos fármacos são causadoras de declínio na produtividade dos rebanhos ovinos no Nordeste do Brasil. Objetivou-se avaliar a eficácia “in vitro” de Amitraz 12,5%, Cipermetrina 15% e Ivermectina 0,5 %
Vanessa Maria de Sales Duarte +12 more
doaj +1 more source
Symposium 9: Beyond lifestyle changes. Pharmacological approach
Revista de la Sociedad Argentina de Diabetes, 2022 The prevalence of overweight and obesity in pediatrics has increased drastically in recent decades. This leads to a greater cardiometabolic, oncological, psychiatric burden and in the quality of life in adulthood.
Lidia Caracotche
doaj +1 more source
Revista de la Sociedad Argentina de Diabetes, 2022 Diabetes is one of the fastest growing diseases all over the world. However, the current therapeutic strategies have not been able to stop neither its progressive course nor its complications. One possible explanation might be that the diabetes diagnosis
Matías Re
doaj +1 more source
Assessment of mutations on RBD in the Spike protein of SARS-CoV-2 Alpha, Delta and Omicron variants
Scientific Reports, 2022 The severe acute respiratory syndrome (SARS) coronavirus 2 (CoV-2) variant Omicron spread more rapid than the other variants of SARS-CoV-2 virus. Mutations on the Spike (S) protein receptor-binding domain (RBD) are critical for the antibody resistance ...
Clauber Henrique Souza da Costa +3 more
doaj +1 more source
BMC Complementary Medicine and Therapies, 2020 Background Currently there is a high prevalence of humor disorders such as anxiety and depression throughout the world, especially concerning advanced age patients. Aniba riparia (Nees) Mez.
Sócrates Golzio dos Santos +9 more
doaj +1 more source
Synthesis and antimycobacterial evaluation of new gem- difluorohydrazides
Orbital: The Electronic Journal of Chemistry, 2012 Several gem-difluorohydrazides were prepared by the addition of nitrogen nucleophiles to N-acetyl-2,2-gem-difluoroxindoles substituted in position 5. Initially, commercial isatin was N-acetylated using acetic anhydride.
Frederico S. C. Branco +4 more
doaj +1 more source