Development of three-colour FRET cascade for force sensing of the putative RIAM-vinculin interaction in fibroblasts. [PDF]
Treacy CA +6 more
europepmc +1 more source
Bacteriophage P22 Virus‐Like Particles as Nanoscale Protein Scaffolds for Plant Synthetic Biology
ABSTRACT Advancing the utility of plant synthetic biology requires the continued development of protein engineering tools. Self‐assembling protein compartments, such as virus‐like particles (VLPs), provide versatile scaffolds for synthetic biology. However, few plant‐expressed VLPs have demonstrated broad amenability to protein engineering, restricting
Maxim D. Harding +5 more
wiley +1 more source
Thermoresponsive artificial light-harvesting system with temperature-gated cascade energy transfer and photocatalysis. [PDF]
Wu Z, Hu M, Sun G, Xiao T.
europepmc +1 more source
Sugars as Central Integrators of Plant Immunity and Stress Responses
ABSTRACT Sugars are fundamental metabolites that sustain plant growth and development, but accumulating evidence demonstrates that they also function as regulatory hubs in plant defence. In this review, we synthesise current knowledge on how carbohydrate dynamics coordinate metabolism, signalling, and structural responses to shape plant resistance ...
Anna Wlazło +2 more
wiley +1 more source
Characterization of Ligand Binding in Human Serum Albumin from Atomistic Energy Transfer Simulations. [PDF]
Ergün Ö +4 more
europepmc +1 more source
Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins +23 more
wiley +1 more source
Astrocytic EAAT‐2 Upregulation Supports Neuro‐Axonal Homeostasis in Chronic Inflammatory CNS Lesions
Inflammatory CNS lesions increase extracellular glutamate. Astrocytic EAAT regulation controls glutamate clearance, stabilizes axonal Ca2+ homeostasis, and determines neurite survival during chronic neuroinflammation. ABSTRACT Neuronal loss in multiple sclerosis (MS) is a key factor in the progression of disability.
Luise Reukauf +9 more
wiley +1 more source
Preparation and Photophysical Study of Rhodamine-Perylenebisimide Electron Donor-Acceptor Dyad/Triads Containing Flexible Linkers. [PDF]
Guan X, Bai H, Zhao J, Wan Y.
europepmc +1 more source
ABSTRACT α1‐Adrenoceptors are an important drug target in benign prostatic hyperplasia (BPH) and have been intensively studied at the expression level, but their posttranslational regulation in the prostate is widely unknown. Here we examined modulation of prostate smooth muscle contractions by inhibitors for RabGTPases, which are involved in ...
Luca Troffer +9 more
wiley +1 more source
Ultralong organic room-temperature phosphorescence of tetraphenylene <i>via</i> lactose functionalization and chromophore isolation. [PDF]
Niu X +8 more
europepmc +1 more source

