Results 31 to 40 of about 13,129,737 (272)
Possible regulation of caveolar endocytosis and flattening by phosphorylation of F-BAR domain protein PACSIN2/Syndapin II. [PDF]
Bioarchitecture, 2015 Caveolae are flask-shaped invaginations of the plasma membrane. The BAR domain proteins form crescent-shaped dimers, and their oligomeric filaments are considered to form spirals at the necks of invaginations, such as clathrin-coated pits and caveolae.
Senju Y, Suetsugu S.
europepmc +4 more sources
BAR Proteins PSTPIP1/2 Regulate Podosome Dynamics and the Resorption Activity of Osteoclasts. [PDF]
PLoS ONE, 2016 Bone resorption in vertebrates relies on the ability of osteoclasts to assemble F-actin-rich podosomes that condense into podosomal belts, forming sealing zones.
Martin Sztacho +5 more
doaj +1 more source
Purification, crystallization and preliminary X-ray analysis of the inverse F-BAR domain of the human srGAP2 protein. [PDF]
Acta Crystallogr F Struct Biol Commun, 2014 Bin-Amphiphysin-Rvs (BAR) domain proteins play essential roles in diverse cellular processes by inducing membrane invaginations or membrane protrusions. Among the BAR superfamily, the `classical' BAR and Fes/CIP4 homology BAR (F-BAR) subfamilies of proteins usually promote membrane invaginations, whereas the inverse BAR (I-BAR) subfamily generally ...
Wang H, Zhang Y, Zhang Z, Jin WL, Wu G.
europepmc +4 more sources
Simulation of Membrane Sculpting by EFC F-BAR Domain Lattices [PDF]
Biophysical Journal, 2010 Cells, during cellular morphogenesis, are dynamically sculpted into different compartments by membranes with the help of proteins. The BAR domain is one of the conserved protein domains that is involved in shaping cellular membranes in vivo, and is observed to induce tubule formation from liposomes in vitro.
Yu, Hang +3 more
openaire +1 more source
Cell Reports, 2021 Summary: Membrane curvature recruits Bin-Amphiphysin-Rvs (BAR)-domain proteins and induces local F-actin assembly, which further modifies the membrane curvature and dynamics. The downstream molecular pathway in vivo is still unclear. Here, we show that a
Tushna Kapoor +3 more
doaj +1 more source
eLife, 2023 The F-BAR protein Cdc15 is essential for cytokinesis in Schizosaccharomyces pombe and plays a key role in attaching the cytokinetic ring (CR) to the plasma membrane (PM).
Rahul Bhattacharjee +7 more
doaj +1 more source
F-BAR/EFC Domain Proteins: Some Assembly Required [PDF]
Developmental Cell, 2015 Polymeric spirals of crescent-shaped BAR-domain superfamily proteins are touted to girdle eukaryotic phospholipid bilayers into narrow tubules for trafficking and membrane remodeling events. But McDonald et al. (2015) in this issue of Developmental Cell question whether this broadly held view and conceptually appealing mechanism for membrane sculpting ...
openaire +2 more sources
Simulations of an F-BAR domain on a flat membrane
, 2020 F-BAR domain on a flat membrane, 2 ...
Javanainen, Matti
core +1 more source
Computer Simulation of Membrane Tubulation by EFC F-BAR Domain Lattices [PDF]
Biophysical Journal, 2012 Cells are dynamically sculpted into many types of compartments by cellular membranes, in some cases with the help of BAR domain proteins. BAR domain proteins act under in vitro conditions are found to induce formation of tubules. We have seen in coarse-grained molecular dynamics simulation stretching over 100 microseconds how a flat membrane is curved ...
Yu, Hang +3 more
openaire +1 more source
Membrane-Sculpting BAR Domains Generate Stable Lipid Microdomains
Cell Reports, 2013 Bin-Amphiphysin-Rvs (BAR) domain proteins are central regulators of many cellular processes involving membrane dynamics. BAR domains sculpt phosphoinositide-rich membranes to generate membrane protrusions or invaginations.
Hongxia Zhao +6 more
doaj +1 more source