Results 51 to 60 of about 16,274,002 (260)
A perfectoid duality between M-theory and F-theory
We present a non-singular, definition-level formulation of F-theory by replacing the traditional shrinking-fiber limit of M-theory with compactification on a tower-completed circle described using perfectoid geometry and condensed mathematics.
Arshid Shabir +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Orientifold limits of singular F-theory vacua
We construct global orientifold limits of singular F-theory vacua whose associated gauge groups are SO(3), SO(5), SO(6), F4, SU(4), and Spin(7). For each limit we show a universal tadpole relation is satisfied, which is a homological identity whose ...
James Fullwood, Dongxu Wang
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
F-theory with hyperelliptic fibrations
We discuss the role of hyperelliptic fibrations in F-theory. For each even integer n we give a noncompact Calabi-Yau threefold X containing a hyperelliptically fibered surface Y, such that X and Y are homotopy equivalent and c 2(X) = n.
E. Ballico +3 more
doaj +1 more source
Vortex spin-torque oscillator stabilized by phase locked loop using integrated circuits
Spin-torque nano-oscillators (STO) are candidates for the next technological implementation of spintronic devices in commercial electronic systems.
Martin Kreissig +11 more
doaj +1 more source
Orders of vanishing and U(1) charges in F-theory
Many interesting questions about F-theory models, including several concerning the F-theory swampland, involve massless matter charged under U(1) gauge symmetries. It is therefore important to better understand the geometric properties of F-theory models
Nikhil Raghuram, Andrew P. Turner
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Holomorphic anomalies, fourfolds and fluxes
We investigate holomorphic anomalies of partition functions underlying string compactifications on Calabi-Yau fourfolds with background fluxes. For elliptic fourfolds the partition functions have an alternative interpretation as elliptic genera of N = 1 ...
Seung-Joo Lee +3 more
doaj +1 more source

