Results 61 to 70 of about 16,274,002 (260)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

R-parity violation in F-theory [PDF]

open access: yes, 2016
We discuss R-parity violation (RPV) in semi-local and local F-theory constructions. We first present a detailed analysis of all possible combinations of RPV operators arising from semi-local F-theory spectral cover constructions, assuming an $SU(5)$ GUT.
Stephen F. King   +9 more
core   +1 more source

Electromagnetic Near-Field Inhomogeneity Reduction for Image Acquisition Optimization in High-Resolution Multi-Channel Magnetic Resonance Imaging (MRI) Systems

open access: yesIEEE Access, 2017
This paper is a study of the inhomogeneity reduction for near-field acquisition in high-resolution magnetic resonance imaging (MRI) systems. The acquisition homogeneity in MRI imaging modality is an open issue concerning the optimal MRI image generation ...
Pablo Padilla   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

F-theory and orientifolds

open access: yes, 1996
By analyzing F-theory on K3 near the orbifold limit of K3 we establish the equivalence between F-theory on K3 and an orientifold of type IIB on T2, which in turn is related by a T-duality transformation to type I theory on T2.
Sen, Ashoke
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

On topological F-theory [PDF]

open access: yes, 2005
We consider the construction of a topological version of F-theory on a particular Spin(7) 8-manifold which is a Calabi-Yau 3-fold times a 2-torus. We write an action for this theory in eight dimensions and reduce it to lower dimensions using Hitchin's
Medeiros, Paul de   +6 more
core   +1 more source

Zoology of complex threefold bases in F-theory

open access: yes, 2018
I'm going to present algorithms that explicitly generate a large number of topologically distinct smooth toric threefold bases used in 4D F-theory compactification. We found inherent patterns in these bases although they are seemingly random.
Wang, Yinan
core   +1 more source

The gravitational sector of 2d (0, 2) F-theory vacua

open access: yesJournal of High Energy Physics, 2017
F-theory compactifications on Calabi-Yau fivefolds give rise to two-dimensional N = (0, 2) supersymmetric field theories coupled to gravity. We explore the dilaton supergravity defined by the moduli sector of such compactifications.
Craig Lawrie   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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