Results 61 to 70 of about 16,274,002 (260)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
R-parity violation in F-theory [PDF]
We discuss R-parity violation (RPV) in semi-local and local F-theory constructions. We first present a detailed analysis of all possible combinations of RPV operators arising from semi-local F-theory spectral cover constructions, assuming an $SU(5)$ GUT.
Stephen F. King +9 more
core +1 more source
This paper is a study of the inhomogeneity reduction for near-field acquisition in high-resolution magnetic resonance imaging (MRI) systems. The acquisition homogeneity in MRI imaging modality is an open issue concerning the optimal MRI image generation ...
Pablo Padilla +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
By analyzing F-theory on K3 near the orbifold limit of K3 we establish the equivalence between F-theory on K3 and an orientifold of type IIB on T2, which in turn is related by a T-duality transformation to type I theory on T2.
Sen, Ashoke
core +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
We consider the construction of a topological version of F-theory on a particular Spin(7) 8-manifold which is a Calabi-Yau 3-fold times a 2-torus. We write an action for this theory in eight dimensions and reduce it to lower dimensions using Hitchin's
Medeiros, Paul de +6 more
core +1 more source
Zoology of complex threefold bases in F-theory
I'm going to present algorithms that explicitly generate a large number of topologically distinct smooth toric threefold bases used in 4D F-theory compactification. We found inherent patterns in these bases although they are seemingly random.
Wang, Yinan
core +1 more source
The gravitational sector of 2d (0, 2) F-theory vacua
F-theory compactifications on Calabi-Yau fivefolds give rise to two-dimensional N = (0, 2) supersymmetric field theories coupled to gravity. We explore the dilaton supergravity defined by the moduli sector of such compactifications.
Craig Lawrie +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

