Results 1 to 10 of about 131,324 (287)

Antimetastatic Effects of Ganoderma lucidum Polysaccharide Peptide on B16-F10-luc-G5 Melanoma Mice With Sleep Fragmentation

Frontiers in Pharmacology, 2021
Ganoderma lucidum (Lingzhi) polysaccharide peptide (GL-pp) is a component of the globally acknowledged traditional Chinese medicine Ganoderma lucidum; Ganoderma lucidum is known for its sedative, hypnotic, immune regulatory, antitumor, and other ...
Haocheng Xian, Jiayi Li, Yimeng Zhang, Ditian Li, Yinan Zhu, Siyan Li, Zhelun Tan, Zhibin Lin, Xuejun Li, Yan Pan   +9 more
doaj   +2 more sources

Comparison of the cytotoxic effects of different fractions of Artemisia ciniformis and Artemisia biennis on B16/F10, PC3 and MCF7 Cells

Research in Pharmaceutical Sciences, 2020
Background and purpose: Artemisia is one of the well-known herbal medicinal plants for antimicrobial, insecticidal, antioxidant, and antimalarial activities. The antiproliferative effects of dichloromethane extracts of Artemisia biennis (A.
Elham Ramazani, Zahra Tayarani-Najaran, Yalda Shokoohinia, Mahdi Mojarrab   +3 more
doaj   +2 more sources

Discrepancy between international normalized ratio measurements in a heterozygous carrier of F10:p.Gly244Arg with recurrent venous thromboembolism: a case report [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: The international normalized ratio (INR) is designed to monitor vitamin K antagonist (VKA) treatment. Before patients start a self-managing VKA program, parallel measurements are conducted to compare point-of-care testing (POCT) INR with ...
Nikolaj Julian Skrøder Nytofte, Emil List Larsen   +1 more
doaj   +2 more sources

Celastrol inhibits mouse B16-F10 melanoma cell survival by regulating the PI3K/AKT/mTOR signaling pathway and repressing HIF-1α expression

Discover Oncology
Objective Melanoma, with its high degree of malignancy, stands as one of the most dangerous skin cancers and remains the primary cause of death from skin cancer.
Ping Zhao, Xing-Bo He, Xin-Yue Chen, Zhang-Long Li, Wen-Jia Xing, Wei Liu, Cong Ren, Xu-Dong Han, Bin Guo   +8 more
doaj   +2 more sources

Development of a Curcumin-Loaded Hyaluronic Acid Nanogel Formulation Using Wet Granulation Method for Enhanced Dissolution and Stability [PDF]

Gels
Curcumin is widely recognized for its various pharmacological properties, including antioxidant, anti-inflammatory, and anti-tumor activities. Nevertheless, the development of curcumin as a therapeutic agent is impeded by its limited oral bioavailability,
Natkhanang Mookkie Boonpetcharat, May Thu Thu Kyaw, Veerakiet Boonkanokwong, Jittima Amie Luckanagul   +3 more
doaj   +2 more sources

Remote cortical perturbation dynamically changes the network solutions to given tactile inputs in neocortical neurons

iScience, 2022
Summary: The neocortex has a globally encompassing network structure, which for each given input constrains the possible combinations of neuronal activations across it. Hence, its network contains solutions.
Leila Etemadi, Jonas M.D. Enander, Henrik Jörntell   +2 more
doaj   +1 more source

Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models

Scientific Reports, 2023
Metastasis is the leading cause of mortality in cancer patients. L-type amino acid transporter 1 (LAT1, SLC7A5) is a Na^+-independent neutral amino acid transporter highly expressed in various cancers to support their growth.
Zitong Shi, K. Kaneda-Nakashima, Ryuichi Ohgaki, Minhui Xu, Hiroki Okanishi, H. Endou, S. Nagamori, Y. Kanai   +7 more
semanticscholar   +1 more source

An in vitro investigation of l‐kynurenine, quinolinic acid, and kynurenic acid on B16 F10 melanoma cell cytotoxicity and morphology

Cell Biochemistry and Function, 2023
The metastatic behavior of melanoma has accentuated the need for specific therapy targets. Compounds, namely l‐kynurenine ( l‐kyn), quinolinic acid (Quin), and kynurenic acid (KA) previously displayed antiproliferative and cytotoxic effects in vitro ...
C. Basson, J. Serem, Y. Hlophe, P. Bipath   +3 more
semanticscholar   +1 more source

Calcitriol Inhibits Proliferation and Potentially Induces Apoptosis in B16–F10 Cells

Medical science monitor basic research, 2022
Background Melanoma is one of the most aggressive types of cancer and it has shown a remarkable surge in incidence during the last 50 years. Melanoma has been projected to be continuously rising in the future.
Eva Sutedja, Daniar Amarassaphira, H. Goenawan, Y. Pratiwi, N. Sylviana, Budi Setiabudiawan, O. Suwarsa, R. Judistiani, U. Supratman, Ronny Lesmana   +9 more
semanticscholar   +1 more source

Sesquiterpenoids from the Stem Bark of Aglaia simplicifolia and Their Cytotoxic Activity against B16-F10 Melanoma Skin Cancer Cell

Indonesian Journal of Chemistry, 2021
Four sesquiterpenoid derivatives, i.e., 4β,10α-dihydroxyaromadendrane (1), caryophyllenol-II (2), senecrassidiol (3), and clovane-2β,9α-diol (4) have been isolated from the stem bark of Aglaia simplicifolia.
Ghina Izdihar, Al Arofatus Naini, D. Harneti, R. Maharani, N. Nurlelasari, T. Mayanti, A. Safari, K. Farabi, U. Supratman, M. N. Azmi, Y. Shiono   +10 more
semanticscholar   +1 more source