Results 21 to 30 of about 23,384 (181)
Adjustment for Inconsistency in Adaptive Phase 2/3 Designs With Dose Optimization. [PDF]
ABSTRACT Adaptive Phase 2/3 designs hold great promise in contemporary oncology drug development, especially when limited data from Phase 1 dose‐finding is insufficient for identifying an optimal dose. However, inconsistent results between Phase 2 and Phase 3 may raise regulatory and practical concerns.
Chen C, Huang M, Zhang X.
europepmc +2 more sources
The tiny globulettes in the Carina Nebula [PDF]
Small molecular cloudlets are abundant in many H II regions surrounding newborn stellar clusters. In optical images these so-called globulettes appear as dark silhouettes against the bright nebular background.
Gahm, Gösta, Grenman, Tiia
core +1 more source
Intracellular Sequestration of the NKG2D Ligand MIC B by Species F Adenovirus
The enteric human adenoviruses of species F (HAdVs-F), which comprise HAdV-F40 and HAdV-F41, are significant pathogens that cause acute gastroenteritis in children worldwide.
Edson R. A. Oliveira +2 more
doaj +1 more source
Adenovirus (HAdV) F41 is a common cause of gastroenteritis and has rarely been reported associated with disseminated disease. In this report, an adult patient with a history of ulcerative colitis, cryptogenic cirrhosis, stage III adenocarcinoma, high ...
Amary Fall +6 more
doaj +1 more source
Exchange rate uncertainty and the connectedness of inflation
In this study, we examine the connectedness of exchange rate uncertainty and inflation. In an economy with a flexible exchange rate, price rigidities can lead importers to carry exchange rate risk and they impose a premium for the risk they face by ...
Sadettin Haluk Çitçi, Hüseyin Kaya
doaj +1 more source
Sustainable development is a global requirement, due to extensive economic and environmental issues, which requires research emphasis. Thus, the purpose of this study is to investigate the effect of sustainable supply chain management (SSCM) practices of
Sumian Peng
doaj +1 more source
The atmospheric response to a thermohaline circulation collapse: scaling relations for the Hadley circulation and the response in a coupled climate model [PDF]
The response of the tropical atmosphere to a collapse of the thermohaline circulation (THC) is investigated by comparing two 5-member ensemble runs with a coupled climate model (CCM), the difference being that in one ensemble a hosing experiment was ...
Broccoli +31 more
core +1 more source
Testing the Twin Deficit Hypothesis: Evidence from the Republic of North Macedonia
An econometric analysis of the twin deficit hypothesis is of special importance for the Republic of North Macedonia in view of its perspective membership in the European Union and from the point of view of its macroeconomic stability in the long run.
Bucevska Vesna
doaj +1 more source
Dirac-K\"ahler particle in Riemann spherical space: boson interpretation [PDF]
In the context of the composite boson interpretation, we construct the exact general solution of the Dirac--K\"ahler equation for the case of the spherical Riemann space of constant positive curvature, for which due to the geometry itself one may expect ...
Florea, O. +3 more
core +1 more source
Commodity prices, bank balance sheets and macroprudential policies in small open economies
How important are liability dollarization in the transmission of commodity shocks on business cycles? To address this question, we developed a small open economy DSGE model with a banking sector and financial friction.
Alfredo Villca
doaj +1 more source

