Results 181 to 190 of about 3,414,366 (288)

Sellés, J. F. (2020). 33 virtudes humanas según Leonardo Polo. Pamplona, EUNSA, 446 pp.

Estudios sobre Educación, 2021
Joaquín León
doaj  

'Home Is Where You Are Together': Qualitative Systematic Review and Meta-Synthesis of Homeless People's Description of Home. [PDF]

Health Expect
Thornhill L, Sellar B, Hernandez GR, Murray CM.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Impact of chemotherapy and immunotherapy on survival in pediatric primary diffuse leptomeningeal melanomatosis: a systematic review and pooled survival analysis. [PDF]

Childs Nerv Syst
Shah KH, Guerrero-Ocampo MJ, Flecha IG, Roach CS, Vazquez S, Servián D, Lu VM.   +6 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Active surveillance of highly suspicious thyroid nodules in the isthmus compared with non-isthmus locations: a multicenter retrospective study. [PDF]

Front Endocrinol (Lausanne)
Hu Y, Zhou W, Li C, Zhang L, Zhan W.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Intrathecal Nalbuphine Versus Other Opioids as Adjuvant to 0.5% Hyperbaric Bupivacaine in Caesarean Section: A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Theodorou-Kanakari A, Karathanasi S, Lykoudis PM, Rekatsina M, Lelekaki E, Gavriilaki M, Kouki P.   +6 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

IL-9 and Blimp-1 protect the transcriptional identity of group 2 innate lymphocytes in allergic asthma. [PDF]

Nat Immunol
Zheng Y, Giri S, Zhang J, Chen Y, Yang A, Kale SL, Beeravolu H, Pannucci A, Marinov AD, Tilstra JS, He K, Creech A, Schwartz DM, Gottschalk RA, Bouladoux N, Belkaid Y, Cillo AR, Ray A, Poholek AC.   +18 more
europepmc   +1 more source