Results 101 to 110 of about 1,258,397 (284)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Robust competitive facility location model with uncertain demand types. [PDF]
PLoS One, 2022 Yu W.
europepmc +1 more source
Capacitated facility location: Valid inequalities and facets [PDF]
Location Theory;Optimization;Capacity ...
Aardal, K.I., Pochet, Y., Wolsey, L.A.
core +1 more source
Online facility location [PDF]
Proceedings 42nd IEEE Symposium on Foundations of Computer Science, 2001 We consider the online variant of facility location, in which demand points arrive one at a time and we must maintain a set of facilities to service these points. We provide a randomized online O(1)-competitive algorithm in the case where points arrive in random order.
openaire +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Algorithmic Study of Online Multi-Facility Location Problems. [PDF]
SN Comput Sci, 2022 Markarian C, Kassar AN, Yunis M.
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Solving a Facility Location Problem by Three Multi-Criteria Decision Making Methods [PDF]
International Journal of Research in Industrial Engineering, 2014 Selecting the most appropriate and optimal facility location for a new organization or expansion of an existing location is an important strategic issue.
M. Niyazi, R. Tavakkoli-Moghaddam
doaj
Robust facility location in reverse logistics. [PDF]
Ann Oper Res, 2023 Egri P, Dávid B, Kis T, Krész M.
europepmc +1 more source
New ideas need new space [PDF]
We develop a setting with weak intellectual property rights, where firms' boundaries, location and knowledge spillovers are endogenous. We have two main results.
Diego Rodríguez
core