Results 41 to 50 of about 284,660 (296)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Separation and Purification TechnologyThe integration of crystallisation into membrane distillation has been proposed for brine mining as a method to effectively control primary nucleation which uses the excess supersaturation to create a new crystal phase. However, primary nucleation desaturates the solvent, subsequently introducing competition between crystal growth and nucleation ...
A. Ouda, Y. Bajón-Fernández, E. McAdam
openaire +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Regulation 61-79 hazardous waste management regulations [PDF]
, 2022 This regulation contains procedures for issuing, modifying, revoking and reissuing, or terminating all hazardous waste treatment, storage, and disposal facility permits under these regulations, other than “emergency permits” (see Section 270.61) and ...
South Carolina Department of Health and Environmental Control
core
智慧农业[Significance]In view of the lack of monitoring means of quality influence factors in the production process of characteristic agricultural products with in central and western regions of China, the weak ability of intelligent control, the unclear ...
GUO Wei +4 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
LLRF Control and Synchronization System of the ARES Facility
, 2021 The linear accelerator ARES (Accelerator Research Experiment at SINBAD) is a new research facility at DESY. Electron bunches with a maximum repetition rate of 50 Hz are accelerated up to 155 MeV. The facility aims for ultra-stable sub-femtosecond arrival-
Burkart, Florian +9 more
core +1 more source
LandEffective microclimate regulation and rainwater management have become critical challenges in residential environments. Bioretention (BR) facilities are widely applied low-impact development (LID) measures that provide co-benefits in runoff control and ...
Geang Liu +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Design of a SMART Valve Testbed for Nuclear Thermal Dispatch
EnergiesBy the year 2050, the United States aims to achieve net-zero carbon emissions. To achieve this target, the licensing of the Light Water Reactor (LWR) fleet has been extended for 20 more years.
Anutam Bairagi +5 more
doaj +1 more source